# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4591797 | 14 | IC50 | > | 10 | uM | ALA4417040 | nM | Homo sapiens | |||
2. | ALA4591797 | 14 | Drug recovery | = | 2.7 | % | ALA4417036 | % | ||||
3. | ALA4591797 | 14 | t1/2 | = | 1.12 | hr | ALA4417057 | hr | ||||
4. | ALA4591797 | 14 | Vdss | = | 0.34 | L/Kg | ALA4417056 | L.kg-1 | ||||
5. | ALA4591797 | 14 | CL | = | 0.22 | L/hr/kg | ALA4417055 | mL.min-1.kg-1 | ||||
6. | ALA4591797 | 14 | Ratio | = | 0.07 | ALA4417054 | ||||||
7. | ALA4591797 | 14 | AUC | = | 15 | ng/mL.hr | ALA4417053 | ng.hr.mL-1 | ||||
8. | ALA4591797 | 14 | Fu | = | 1.5 | % | ALA4417052 | |||||
9. | ALA4591797 | 14 | Fu | = | 1.5 | % | ALA4417051 | |||||
10. | ALA4591797 | 14 | Ratio | = | 5 | ALA4417050 | ||||||
11. | ALA4591797 | 14 | permeability | = | 27 | 10'-6 cm/s | ALA4417049 | 10'-6 cm/s | ||||
12. | ALA4591797 | 14 | solubility | = | 48 | ug ml-1 | ALA4417048 | ug.mL-1 | ||||
13. | ALA4591797 | 14 | IC50 | = | 13 | nM | ALA4417039 | 7.89 | nM | Homo sapiens | ||
14. | ALA4591797 | 14 | IC50 | = | 92 | nM | ALA4417038 | 7.04 | nM | Homo sapiens |