Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Assay	Assay Organism
1.	ALA4633161	21; LY3325656	ED80	=	1.6	mg kg-1	ALA4742496		mg kg-1	Mus musculus
2.	ALA4633161	21; LY3325656	ED50	=	0.3	mg kg-1	ALA4742496		mg.kg-1	Mus musculus
3.	ALA4633161	21; LY3325656	Emax	=	109	%	ALA4742495		%	Homo sapiens
4.	ALA4633161	21; LY3325656	EC50	=	43.5	nM	ALA4742494	7.36	nM	Homo sapiens
5.	ALA4633161	21; LY3325656	CL	<	5	%	ALA4627671		%
6.	ALA4633161	21; LY3325656	pKa	=	5.9		ALA4627670
7.	ALA4633161	21; LY3325656	NOAEL	=	180	mg kg-1	ALA4627664		mg kg-1
8.	ALA4633161	21; LY3325656	NOAEL	=	200	mg kg-1	ALA4627663		mg kg-1
9.	ALA4633161	21; LY3325656	permeability	=	13.6	10'-6 cm/s	ALA4627662		10'-6 cm/s
10.	ALA4633161	21; LY3325656	solubility	>	2	mg/ml	ALA4627661		ug.mL-1
11.	ALA4633161	21; LY3325656	INH	=	16	%	ALA4627660		%	Homo sapiens
12.	ALA4633161	21; LY3325656	INH	=	11	%	ALA4627659		%	Homo sapiens
13.	ALA4633161	21; LY3325656	INH	=	22	%	ALA4627658		%	Homo sapiens
14.	ALA4633161	21; LY3325656	F	=	78	%	ALA4627657		%
15.	ALA4633161	21; LY3325656	Vdss	=	1.3	L/Kg	ALA4627656		L.kg-1
16.	ALA4633161	21; LY3325656	CL	=	8.4	min/ml/kg	ALA4627655		min/ml/kg
17.	ALA4633161	21; LY3325656	F	=	63	%	ALA4627654		%
18.	ALA4633161	21; LY3325656	Vdss	=	1.1	L/Kg	ALA4627653		L.kg-1
19.	ALA4633161	21; LY3325656	CL	=	22.1	min/ml/kg	ALA4627652		min/ml/kg
20.	ALA4633161	21; LY3325656	Drug metabolism	=	14	%	ALA4627651		%