# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4633246 | 37; DSM502 | TDI | 0 | ALA4605522 | Active | Homo sapiens | |||||
2. | ALA4633246 | 37; DSM502 | Activity | 0 | ALA4605526 | Toxic | ||||||
3. | ALA4633246 | 37; DSM502 | Activity | 0 | ALA4605525 | Toxic | ||||||
4. | ALA4633246 | 37; DSM502 | IC50 | = | 5.5 | uM | ALA4605524 | 5.26 | nM | Homo sapiens | ||
5. | ALA4633246 | 37; DSM502 | IC50 | > | 20 | uM | ALA4605523 | nM | Homo sapiens | |||
6. | ALA4633246 | 37; DSM502 | TDI | 0 | ALA4605521 | Not Active | Homo sapiens | |||||
7. | ALA4633246 | 37; DSM502 | TDI | 0 | ALA4605520 | Not Active | Homo sapiens | |||||
8. | ALA4633246 | 37; DSM502 | TDI | 0 | ALA4605519 | Not Active | Homo sapiens | |||||
9. | ALA4633246 | 37; DSM502 | TDI | 0 | ALA4605518 | Not Active | Homo sapiens | |||||
10. | ALA4633246 | 37; DSM502 | TDI | 0 | ALA4605517 | Not Active | Homo sapiens | |||||
11. | ALA4633246 | 37; DSM502 | TDI | 0 | ALA4605516 | Not Active | Homo sapiens | |||||
12. | ALA4633246 | 37; DSM502 | TDI | 0 | ALA4605515 | Not Active | Homo sapiens | |||||
13. | ALA4633246 | 37; DSM502 | IC50 | > | 20 | uM | ALA4605514 | nM | Homo sapiens | |||
14. | ALA4633246 | 37; DSM502 | PB | = | 76.2 | % | ALA4605513 | % | Homo sapiens | |||
15. | ALA4633246 | 37; DSM502 | Drug metabolism | < | 3 | % | ALA4605511 | % | ||||
16. | ALA4633246 | 37; DSM502 | Drug metabolism | = | 6 | % | ALA4605512 | % | ||||
17. | ALA4633246 | 37; DSM502 | fAUC | = | 1.1 | ug.hr/ml | ALA4605509 | ng.hr.mL-1 | ||||
18. | ALA4633246 | 37; DSM502 | AUCED90 | = | 9 | ug.hr/ml | ALA4605508 | ug.hr/ml | Plasmodium falciparum | |||
19. | ALA4633246 | 37; DSM502 | Activity | = | 97 | % | ALA4605507 | % | Plasmodium falciparum | |||
20. | ALA4633246 | 37; DSM502 | Activity | = | 85 | % | ALA4605506 | % | Plasmodium falciparum |