# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4635482 | 37 | IC50 | = | 0 | uM | ALA5127341 | 10.00 | nM | Homo sapiens | ||
2. | ALA4635482 | 37 | CL | = | 3.12 | L/hr/kg | ALA4619392 | mL.min-1.kg-1 | ||||
3. | ALA4635482 | 37 | Vd | = | 6.63 | L/Kg | ALA4619391 | L.kg-1 | ||||
4. | ALA4635482 | 37 | Activity | 0 | ALA4619390 | Active | Mus musculus | |||||
5. | ALA4635482 | 37 | Activity | 0 | ALA4619389 | Active | Mus musculus | |||||
6. | ALA4635482 | 37 | Activity | 0 | ALA4619384 | Dose-dependent effect | Mus musculus | |||||
7. | ALA4635482 | 37 | Activity | 0 | ALA4619383 | Dose-dependent effect | Mus musculus | |||||
8. | ALA4635482 | 37 | INH | = | 49 | % | ALA4619382 | % | Homo sapiens | |||
9. | ALA4635482 | 37 | INH | = | 50 | % | ALA4619381 | % | Homo sapiens | |||
10. | ALA4635482 | 37 | Ratio IC50 | = | 210 | ALA4619378 | ||||||
11. | ALA4635482 | 37 | IC50 | = | 0.021 | nM | ALA4619377 | 10.68 | nM | |||
12. | ALA4635482 | 37 | IC50 | = | 0.045 | uM | ALA4619376 | 7.35 | nM | Homo sapiens | ||
13. | ALA4635482 | 37 | PB | = | 92.5 | % | ALA4619375 | % | ||||
14. | ALA4635482 | 37 | AUClast | = | 395.2 | nM.hr | ALA4619373 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
15. | ALA4635482 | 37 | Cmax | = | 261 | nM | ALA4619372 | nM | ||||
16. | ALA4635482 | 37 | Tmax | = | 0.25 | hr | ALA4619371 | hr | ||||
17. | ALA4635482 | 37 | t1/2 | = | 1.74 | hr | ALA4619370 | hr | ||||
18. | ALA4635482 | 37 | IC50 | = | 0 | uM | ALA4619369 | 10.00 | nM | Homo sapiens |