# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4636528 | 13n; OFH243 | Selectivity ratio | = | 53 | ALA5239844 | Homo sapiens | |||||
2. | ALA4636528 | 13n; OFH243 | Selectivity ratio | = | 3.6 | ALA5239843 | Homo sapiens | |||||
3. | ALA4636528 | 13n; OFH243 | Ki | = | 0.064 | nM | ALA5239840 | 10.19 | nM | Homo sapiens | ||
4. | ALA4636528 | 13n; OFH243 | Ki | = | 3.4 | nM | ALA5239839 | 8.47 | nM | Homo sapiens | ||
5. | ALA4636528 | 13n; OFH243 | Ki | = | 0.23 | nM | ALA5239838 | 9.64 | nM | Homo sapiens | ||
6. | ALA4636528 | 13n; OFH243 | Stability | = | 74 | % | ALA4605249 | % | ||||
7. | ALA4636528 | 13n; OFH243 | Ratio EC50 | = | 2.5 | ALA4605248 | Homo sapiens | |||||
8. | ALA4636528 | 13n; OFH243 | permeability | 0 | ALA4605244 | Impermeable | ||||||
9. | ALA4636528 | 13n; OFH243 | Ratio | = | 2.2 | ALA4605243 | ||||||
10. | ALA4636528 | 13n; OFH243 | permeability | = | 46.2 | a.u. | ALA4605242 | a.u. | ||||
11. | ALA4636528 | 13n; OFH243 | permeability | = | 99.5 | a.u. | ALA4605241 | a.u. | ||||
12. | ALA4636528 | 13n; OFH243 | Ratio | = | 2.7 | ALA4605240 | ||||||
13. | ALA4636528 | 13n; OFH243 | permeability | = | 9.2 | a.u. | ALA4605239 | a.u. | ||||
14. | ALA4636528 | 13n; OFH243 | permeability | = | 3.5 | a.u. | ALA4605238 | a.u. | ||||
15. | ALA4636528 | 13n; OFH243 | Emax | = | 2.4 | % | ALA4605237 | % | Homo sapiens | |||
16. | ALA4636528 | 13n; OFH243 | EC50 | = | 4.1 | nM | ALA4605235 | 8.39 | nM | Homo sapiens | ||
17. | ALA4636528 | 13n; OFH243 | Emax | < | 3 | % | ALA4605236 | % | Homo sapiens | |||
18. | ALA4636528 | 13n; OFH243 | Emax | = | -13 | % | ALA4605233 | % | Homo sapiens | |||
19. | ALA4636528 | 13n; OFH243 | EC50 | = | 9.3 | nM | ALA4605232 | 8.03 | nM | Homo sapiens | ||
20. | ALA4636528 | 13n; OFH243 | Emax | = | -23 | % | ALA4605231 | % | Homo sapiens |