# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4636553 | 45; DSM538 | PB | = | 74.9 | % | ALA4605513 | % | Homo sapiens | |||
2. | ALA4636553 | 45; DSM538 | CLH | = | 94 | uL/min | ALA4605403 | uL/min | ||||
3. | ALA4636553 | 45; DSM538 | CLH | = | 21 | uL/min | ALA4605402 | uL/min | ||||
4. | ALA4636553 | 45; DSM538 | Kinetic_solubility | = | 25 | ug ml-1 | ALA4605400 | ug.mL-1 | ||||
5. | ALA4636553 | 45; DSM538 | logD | = | 3.3 | ALA4605399 | ||||||
6. | ALA4636553 | 45; DSM538 | IC50 | > | 100 | uM | ALA4605398 | nM | ||||
7. | ALA4636553 | 45; DSM538 | IC50 | > | 100 | uM | ALA4605397 | nM | Rattus norvegicus | |||
8. | ALA4636553 | 45; DSM538 | IC50 | > | 100 | uM | ALA4605396 | nM | Mus musculus | |||
9. | ALA4636553 | 45; DSM538 | EC50 | = | 0.029 | uM | ALA4605392 | 7.54 | nM | Plasmodium falciparum | ||
10. | ALA4636553 | 45; DSM538 | IC50 | > | 100 | uM | ALA4605391 | nM | Homo sapiens | |||
11. | ALA4636553 | 45; DSM538 | IC50 | = | 0.018 | uM | ALA4605390 | 7.75 | nM | |||
12. | ALA4636553 | 45; DSM538 | IC50 | = | 0.033 | uM | ALA4605389 | 7.48 | nM |