Activities

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Activities

Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA4637126	81	pIC50	=	7.4		ALA4611266	7.40		nM	Homo sapiens
2.	ALA4637126	81	IC50	>	40	uM	ALA4611294			nM	Mus musculus
3.	ALA4637126	81	Ratio LC50/IC50	>	40		ALA4611299
4.	ALA4637126	81	Activity		0		ALA4611297		Non-Toxic
5.	ALA4637126	81	Activity		0		ALA4611295		Active		Homo sapiens
6.	ALA4637126	81	Activity	=	55	mg	ALA4611292			mg	Homo sapiens
7.	ALA4637126	81	Activity	=	59	mg	ALA4611291			mg	Homo sapiens
8.	ALA4637126	81	Activity		0		ALA4611288		Non-Toxic
9.	ALA4637126	81	Activity		0		ALA4611287		Non-Toxic
10.	ALA4637126	81	IC50	=	2.1	uM	ALA4611286	5.68		nM	Homo sapiens
11.	ALA4637126	81	INH		0		ALA4611286		Dose-dependent effect	%	Homo sapiens
12.	ALA4637126	81	Activity		0		ALA4611285		Non-Toxic		Homo sapiens
13.	ALA4637126	81	AUC	=	2047	ng.hr/ml	ALA4611284			ng.hr.mL-1
14.	ALA4637126	81	t1/2	=	2.82	hr	ALA4611283			hr
15.	ALA4637126	81	Cmax	=	798	ng/ml	ALA4611282		standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW	nM
16.	ALA4637126	81	t1/2	=	1.58	hr	ALA4611281			hr
17.	ALA4637126	81	Vdss	=	3.32	L/Kg	ALA4611280			L.kg-1
18.	ALA4637126	81	CL	=	28.4	ml/min.kg	ALA4611279			mL.min-1.kg-1
19.	ALA4637126	81	Drug metabolism	=	100	%	ALA4611278			%
20.	ALA4637126	81	Drug metabolism	=	100	%	ALA4611277			%