# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4637258 | 27.HCl | TGI | 0 | ALA4612593 | Active | Homo sapiens | |||||
2. | ALA4637258 | 27.HCl | TGI | = | 106 | % | ALA4612589 | % | Homo sapiens | |||
3. | ALA4637258 | 27.HCl | Activity | 0 | ALA4612590 | Non-Toxic | ||||||
4. | ALA4637258 | 27.HCl | Activity | 0 | ALA4612592 | Non-Toxic | ||||||
5. | ALA4637258 | 27.HCl | Activity | = | 1052 | ml | ALA4612585 | ml | ||||
6. | ALA4637258 | 27.HCl | F | = | 49 | % | ALA4612581 | % | ||||
7. | ALA4637258 | 27.HCl | AUC | = | 9598 | hr.ng/ml | ALA4612580 | ng.hr.mL-1 | ||||
8. | ALA4637258 | 27.HCl | Cmax | = | 3090 | ng/ml | ALA4612579 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
9. | ALA4637258 | 27.HCl | Tmax | = | 0.25 | hr | ALA4612578 | hr | ||||
10. | ALA4637258 | 27.HCl | t1/2 | = | 2.9 | hr | ALA4612577 | hr | ||||
11. | ALA4637258 | 27.HCl | Vdss | = | 1.49 | L/Kg | ALA4612576 | L.kg-1 | ||||
12. | ALA4637258 | 27.HCl | CL | = | 25.5 | ml/min.kg | ALA4612575 | mL.min-1.kg-1 | ||||
13. | ALA4637258 | 27.HCl | AUC | = | 3208 | hr.ng/ml | ALA4612574 | ng.hr.mL-1 | ||||
14. | ALA4637258 | 27.HCl | t1/2 | = | 1.95 | hr | ALA4612573 | hr | ||||
15. | ALA4637258 | 27.HCl | PPB | = | 97.98 | % | ALA4612564 | % | ||||
16. | ALA4637258 | 27.HCl | CLH | = | 6.86 | uL/min | ALA4612563 | uL/min | ||||
17. | ALA4637258 | 27.HCl | t1/2 | = | 202 | min | ALA4612562 | hr | ||||
18. | ALA4637258 | 27.HCl | INH | = | 50.61 | % | ALA4612561 | % | Homo sapiens | |||
19. | ALA4637258 | 27.HCl | INH | = | 14.5 | % | ALA4612560 | % | Homo sapiens | |||
20. | ALA4637258 | 27.HCl | INH | = | 31.79 | % | ALA4612559 | % | Homo sapiens |