| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4637298 | 36; GSK973 | F | = | 87 | % | ALA4622526 | % | ||||
| 2. | ALA4637298 | 36; GSK973 | t1/2 | = | 4.8 | hr | ALA4622525 | hr | ||||
| 3. | ALA4637298 | 36; GSK973 | Vdss | = | 1.3 | L/Kg | ALA4622524 | L.kg-1 | ||||
| 4. | ALA4637298 | 36; GSK973 | CL | = | 0.3 | ml/min.kg | ALA4622523 | mL.min-1.kg-1 | ||||
| 5. | ALA4637298 | 36; GSK973 | CL | = | 3 | ml/min.kg | ALA4622522 | mL.min-1.kg-1 | ||||
| 6. | ALA4637298 | 36; GSK973 | F | = | 48 | % | ALA4622521 | % | ||||
| 7. | ALA4637298 | 36; GSK973 | t1/2 | = | 0.6 | hr | ALA4622520 | hr | ||||
| 8. | ALA4637298 | 36; GSK973 | Vdss | = | 2.1 | L/Kg | ALA4622519 | L.kg-1 | ||||
| 9. | ALA4637298 | 36; GSK973 | CL | = | 4 | ml/min.kg | ALA4622518 | mL.min-1.kg-1 | ||||
| 10. | ALA4637298 | 36; GSK973 | CL | = | 73 | ml/min.kg | ALA4622517 | mL.min-1.kg-1 | ||||
| 11. | ALA4637298 | 36; GSK973 | CLH | < | 0.65 | ml/min | ALA4622514 | ml/min | ||||
| 12. | ALA4637298 | 36; GSK973 | CLH | = | 1.76 | ml/min | ALA4622512 | ml/min | ||||
| 13. | ALA4637298 | 36; GSK973 | pIC50 | = | 7.3 | ALA4622497 | 7.30 | nM | Homo sapiens | |||
| 14. | ALA4637298 | 36; GSK973 | solubility | = | 173 | ug ml-1 | ALA4622503 | ug.mL-1 | ||||
| 15. | ALA4637298 | 36; GSK973 | INH | 0 | ALA4622559 | Not Active | % | Homo sapiens | ||||
| 16. | ALA4637298 | 36; GSK973 | INH | 0 | ALA4622558 | Not Active | % | Homo sapiens | ||||
| 17. | ALA4637298 | 36; GSK973 | INH | 0 | ALA4622557 | Not Active | % | Homo sapiens | ||||
| 18. | ALA4637298 | 36; GSK973 | INH | 0 | ALA4622556 | Not Active | % | Homo sapiens | ||||
| 19. | ALA4637298 | 36; GSK973 | INH | 0 | ALA4622555 | Not Active | % | Homo sapiens | ||||
| 20. | ALA4637298 | 36; GSK973 | INH | 0 | ALA4622554 | Not Active | % | Homo sapiens |
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