# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4638783 | 1b | MRT | = | 1.19 | hr | ALA4628035 | hr | ||||
2. | ALA4638783 | 1b | AUC | = | 127 | ng.hr/ml | ALA4628034 | ng.hr.mL-1 | ||||
3. | ALA4638783 | 1b | AUClast | = | 116 | ng.hr/ml | ALA4628033 | ng.hr.mL-1 | ||||
4. | ALA4638783 | 1b | beta t1/2 | = | 1.64 | hr | ALA4628032 | hr | ||||
5. | ALA4638783 | 1b | Vdss | = | 3.74 | L/Kg | ALA4628031 | L.kg-1 | ||||
6. | ALA4638783 | 1b | CL | = | 3.15 | L/hr/kg | ALA4628030 | mL.min-1.kg-1 | ||||
7. | ALA4638783 | 1b | IC50 | = | 0.491 | uM | ALA4628021 | 6.31 | nM | Homo sapiens | ||
8. | ALA4638783 | 1b | IC50 | = | 1.49 | uM | ALA4628022 | 5.83 | nM | Homo sapiens | ||
9. | ALA4638783 | 1b | IC50 | = | 7.95 | uM | ALA4628023 | 5.10 | nM | Homo sapiens | ||
10. | ALA4638783 | 1b | IC50 | = | 1.51 | uM | ALA4628024 | 5.82 | nM | Homo sapiens | ||
11. | ALA4638783 | 1b | IC50 | = | 4.36 | uM | ALA4628025 | 5.36 | nM | Homo sapiens |