| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4638913 | 18B | PB | 0 | ALA4622220 | Not Active | % | |||||
| 2. | ALA4638913 | 18B | PB | 0 | ALA4622219 | Not Active | % | |||||
| 3. | ALA4638913 | 18B | fIC50 | = | 14 | nM | ALA4622180 | nM | ||||
| 4. | ALA4638913 | 18B | fIC50 | = | 19 | nM | ALA4622179 | nM | Homo sapiens | |||
| 5. | ALA4638913 | 18B | Therm_solubility | = | 85 | mg/ml | ALA4622218 | ug.mL-1 | ||||
| 6. | ALA4638913 | 18B | Activity | 0 | ALA4622217 | Non-Toxic | ||||||
| 7. | ALA4638913 | 18B | IC50 | = | 25 | uM | ALA4622213 | 4.60 | nM | Homo sapiens | ||
| 8. | ALA4638913 | 18B | IC50 | = | 25 | uM | ALA4622211 | 4.60 | nM | Homo sapiens | ||
| 9. | ALA4638913 | 18B | solubility | = | 390 | mg/ml | ALA4622210 | ug.mL-1 | ||||
| 10. | ALA4638913 | 18B | solubility | = | 234 | mg/ml | ALA4622209 | ug.mL-1 | ||||
| 11. | ALA4638913 | 18B | Activity | 0 | ALA4622208 | Non-Toxic | ||||||
| 12. | ALA4638913 | 18B | INH | 0 | ALA4622207 | Tde | % | Mus musculus | ||||
| 13. | ALA4638913 | 18B | INH | 0 | ALA4622207 | Dose-dependent effect | % | Mus musculus | ||||
| 14. | ALA4638913 | 18B | IC50 | = | 40 | nM | ALA4622207 | 7.40 | nM | Mus musculus | ||
| 15. | ALA4638913 | 18B | F | = | 27 | % | ALA4622206 | % | ||||
| 16. | ALA4638913 | 18B | Vdss | = | 0.83 | L/Kg | ALA4622205 | L.kg-1 | ||||
| 17. | ALA4638913 | 18B | beta t1/2 | = | 6.7 | hr | ALA4622204 | hr | ||||
| 18. | ALA4638913 | 18B | CL | = | 3.35 | ml/min.kg | ALA4622203 | mL.min-1.kg-1 | ||||
| 19. | ALA4638913 | 18B | AUC/dose | = | 1383 | hr.kg.ng/ml/mg | ALA4622202 | hr.kg.ng/ml/mg | ||||
| 20. | ALA4638913 | 18B | F | = | 33 | % | ALA4622201 | % |
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