# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4639252 | (P)-15 | Papp | = | 18 | 10'-6 cm/s | ALA4619047 | 10'-6 cm/s | ||||
2. | ALA4639252 | (P)-15 | Papp | = | 1.7 | 10'-6 cm/s | ALA4619046 | 10'-6 cm/s | ||||
3. | ALA4639252 | (P)-15 | CLH | = | 0.36 | L/hr/kg | ALA4619045 | mL.min-1.kg-1 | ||||
4. | ALA4639252 | (P)-15 | CLH | = | 0.08 | L/hr/kg | ALA4619045 | mL.min-1.kg-1 | ||||
5. | ALA4639252 | (P)-15 | IC50 | > | 25 | uM | ALA4619044 | nM | Homo sapiens | |||
6. | ALA4639252 | (P)-15 | pKa | = | 6.1 | ALA4619043 | ||||||
7. | ALA4639252 | (P)-15 | Ratio IC50 | = | 9 | ALA4619041 | ||||||
8. | ALA4639252 | (P)-15 | Ratio IC50 | = | 11 | ALA4619041 | ||||||
9. | ALA4639252 | (P)-15 | Ratio IC50 | = | 49 | ALA4619040 | ||||||
10. | ALA4639252 | (P)-15 | Ratio IC50 | = | 56 | ALA4619040 | ||||||
11. | ALA4639252 | (P)-15 | IC50 | > | 10000 | nM | ALA4619039 | nM | Homo sapiens | |||
12. | ALA4639252 | (P)-15 | IC50 | = | 1464 | nM | ALA4619038 | 5.83 | nM | Homo sapiens | ||
13. | ALA4639252 | (P)-15 | IC50 | = | 84 | nM | ALA4619038 | 7.08 | nM | Homo sapiens | ||
14. | ALA4639252 | (P)-15 | IC50 | = | 107 | nM | ALA4619038 | 6.97 | nM | Homo sapiens | ||
15. | ALA4639252 | (P)-15 | IC50 | > | 10000 | nM | ALA4619037 | nM | Homo sapiens | |||
16. | ALA4639252 | (P)-15 | IC50 | = | 414 | nM | ALA4619037 | 6.38 | nM | Homo sapiens | ||
17. | ALA4639252 | (P)-15 | IC50 | = | 560 | nM | ALA4619037 | 6.25 | nM | Homo sapiens | ||
18. | ALA4639252 | (P)-15 | IC50 | = | 206 | nM | ALA4619036 | 6.69 | nM | Homo sapiens | ||
19. | ALA4639252 | (P)-15 | IC50 | = | 9 | nM | ALA4619036 | 8.05 | nM | Homo sapiens | ||
20. | ALA4639252 | (P)-15 | IC50 | = | 10 | nM | ALA4619036 | 8.00 | nM | Homo sapiens |