# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4639776 | 9 | Activity | 0 | ALA4623776 | Dose-dependent effect | Homo sapiens | |||||
2. | ALA4639776 | 9 | Activity | 0 | ALA4623764 | Dose-dependent effect | Rattus norvegicus | |||||
3. | ALA4639776 | 9 | Cmax | = | 85.29 | ng/ml | ALA4623765 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
4. | ALA4639776 | 9 | Tmax | = | 0.31 | hr | ALA4623766 | hr | ||||
5. | ALA4639776 | 9 | AUC | = | 330.2 | ng.hr/ml | ALA4623767 | ng.hr.mL-1 | ||||
6. | ALA4639776 | 9 | AUC | = | 208.8 | ng.hr/ml | ALA4623768 | ng.hr.mL-1 | ||||
7. | ALA4639776 | 9 | t1/2 | = | 2.43 | hr | ALA4623769 | hr | ||||
8. | ALA4639776 | 9 | t1/2 | = | 2.16 | hr | ALA4623770 | hr | ||||
9. | ALA4639776 | 9 | CL | = | 917.7 | ml/hr/kg | ALA4623771 | mL.min-1.kg-1 | ||||
10. | ALA4639776 | 9 | Vdss | = | 1.59 | L/Kg | ALA4623772 | L.kg-1 | ||||
11. | ALA4639776 | 9 | F | = | 19 | % | ALA4623773 | % | ||||
12. | ALA4639776 | 9 | Activity | = | 2.34 | g | ALA4623752 | g | Rattus norvegicus | |||
13. | ALA4639776 | 9 | Activity | = | 2.79 | g | ALA4623774 | g | Rattus norvegicus | |||
14. | ALA4639776 | 9 | Activity | = | 3.49 | g | ALA4623775 | g | Rattus norvegicus | |||
15. | ALA4639776 | 9 | FC | = | 269 | ALA4623754 | Homo sapiens | |||||
16. | ALA4639776 | 9 | FC | = | 110 | ALA4623762 | Rattus norvegicus | |||||
17. | ALA4639776 | 9 | EC30 | > | 10000 | nM | ALA4623763 | nM | Homo sapiens | |||
18. | ALA4639776 | 9 | FC | = | 2.3 | ALA4623753 | Homo sapiens | |||||
19. | ALA4639776 | 9 | FC | = | 1.6 | ALA4623757 | Rattus norvegicus | |||||
20. | ALA4639776 | 9 | FC | = | 0.7 | ALA4623760 | Rattus norvegicus |