# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4641109 | 37 | INH | = | 43 | % | ALA4614770 | % | Mus musculus | |||
2. | ALA4641109 | 37 | INH | = | 35 | % | ALA4614769 | % | Mus musculus | |||
3. | ALA4641109 | 37 | F | = | 83 | % | ALA4614766 | % | ||||
4. | ALA4641109 | 37 | AUClast | = | 9.8 | uM.hr | ALA4614764 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
5. | ALA4641109 | 37 | MRT | = | 2.4 | hr | ALA4614763 | hr | ||||
6. | ALA4641109 | 37 | t1/2 | = | 5.6 | hr | ALA4614762 | hr | ||||
7. | ALA4641109 | 37 | Vdss | = | 4.4 | L/Kg | ALA4614761 | L.kg-1 | ||||
8. | ALA4641109 | 37 | CL | = | 10 | ml/min.kg | ALA4614760 | mL.min-1.kg-1 | ||||
9. | ALA4641109 | 37 | IC50 | = | 0.12 | uM | ALA4614754 | 6.92 | nM | Mus musculus | ||
10. | ALA4641109 | 37 | IC50 | = | 0.24 | uM | ALA4614753 | 6.62 | nM | Homo sapiens | ||
11. | ALA4641109 | 37 | IC50 | = | 0.018 | uM | ALA4614752 | 7.75 | nM | Homo sapiens |