# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4641633 | 27 | IC50 | > | 6.5 | uM | ALA4622262 | nM | Homo sapiens | |||
2. | ALA4641633 | 27 | IC50 | > | 6.5 | uM | ALA4622263 | nM | Homo sapiens | |||
3. | ALA4641633 | 27 | IC50 | > | 6.5 | uM | ALA4622264 | nM | Homo sapiens | |||
4. | ALA4641633 | 27 | IC50 | > | 6.5 | uM | ALA4622265 | nM | Homo sapiens | |||
5. | ALA4641633 | 27 | IC50 | = | 0.002 | uM | ALA4622261 | 8.68 | nM | Homo sapiens | ||
6. | ALA4641633 | 27 | INH | 0 | ALA4622260 | Dose-dependent effect | % | Mus musculus | ||||
7. | ALA4641633 | 27 | Tmax | = | 1 | hr | ALA4622259 | hr | ||||
8. | ALA4641633 | 27 | Tmax | = | 0.8 | hr | ALA4622258 | hr | ||||
9. | ALA4641633 | 27 | Cmax/dose | = | 248 | nM | ALA4622257 | nM | ||||
10. | ALA4641633 | 27 | Cmax/dose | = | 129 | nM | ALA4622256 | nM | ||||
11. | ALA4641633 | 27 | F | = | 53 | % | ALA4622255 | % | ||||
12. | ALA4641633 | 27 | F | = | 88 | % | ALA4622254 | % | ||||
13. | ALA4641633 | 27 | AUC/dose | = | 935 | nM.hr | ALA4622253 | nM.hr | ||||
14. | ALA4641633 | 27 | AUC/dose | = | 1008 | nM.hr | ALA4622252 | nM.hr | ||||
15. | ALA4641633 | 27 | AUC/dose | = | 1765 | nM.hr | ALA4622251 | nM.hr | ||||
16. | ALA4641633 | 27 | AUC/dose | = | 1152 | nM.hr | ALA4622250 | nM.hr | ||||
17. | ALA4641633 | 27 | MRT | = | 1.6 | hr | ALA4622249 | hr | ||||
18. | ALA4641633 | 27 | MRT | = | 2 | hr | ALA4622248 | hr | ||||
19. | ALA4641633 | 27 | t1/2 | = | 1.6 | hr | ALA4622247 | hr | ||||
20. | ALA4641633 | 27 | t1/2 | = | 4.6 | hr | ALA4622246 | hr |