| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4642128 | 1c | Imax | >= | 35 | % | ALA4628057 | % | Homo sapiens | |||
| 2. | ALA4642128 | 1c | INH | 0 | ALA4628056 | Dose-dependent effect | % | |||||
| 3. | ALA4642128 | 1c | MRT | = | 2.16 | hr | ALA4628035 | hr | ||||
| 4. | ALA4642128 | 1c | AUC | = | 204 | ng.hr/ml | ALA4628034 | ng.hr.mL-1 | ||||
| 5. | ALA4642128 | 1c | AUClast | = | 189 | ng.hr/ml | ALA4628033 | ng.hr.mL-1 | ||||
| 6. | ALA4642128 | 1c | beta t1/2 | = | 2.21 | hr | ALA4628032 | hr | ||||
| 7. | ALA4642128 | 1c | Vdss | = | 4.3 | L/Kg | ALA4628031 | L.kg-1 | ||||
| 8. | ALA4642128 | 1c | CL | = | 1.97 | L/hr/kg | ALA4628030 | mL.min-1.kg-1 | ||||
| 9. | ALA4642128 | 1c | IC50 | = | 0.758 | uM | ALA4628021 | 6.12 | nM | Homo sapiens | ||
| 10. | ALA4642128 | 1c | IC50 | = | 2.88 | uM | ALA4628022 | 5.54 | nM | Homo sapiens | ||
| 11. | ALA4642128 | 1c | IC50 | > | 10 | uM | ALA4628023 | nM | Homo sapiens | |||
| 12. | ALA4642128 | 1c | IC50 | > | 10 | uM | ALA4628024 | nM | Homo sapiens | |||
| 13. | ALA4642128 | 1c | IC50 | > | 10 | uM | ALA4628025 | nM | Homo sapiens |
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