Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay	Assay Organism
1.	Iptacopan hydrochloride	41.HCl	Tmax	=	0.8	hr	ALA4614812	hr
2.	Iptacopan hydrochloride	41.HCl	Cmax/dose	=	2200	nM	ALA4614811	nM
3.	Iptacopan hydrochloride	41.HCl	F	=	60	%	ALA4614810	%
4.	Iptacopan hydrochloride	41.HCl	AUC/dose	=	12700	nM.hr	ALA4614809	nM.hr
5.	Iptacopan hydrochloride	41.HCl	AUC/dose	=	21000	nM.hr	ALA4614808	nM.hr
6.	Iptacopan hydrochloride	41.HCl	MRT	=	5.5	hr	ALA4614807	hr
7.	Iptacopan hydrochloride	41.HCl	t1/2	=	5.6	hr	ALA4614806	hr
8.	Iptacopan hydrochloride	41.HCl	Vdss	=	0.6	L/Kg	ALA4614805	L.kg-1
9.	Iptacopan hydrochloride	41.HCl	CL	=	2	ml/min.kg	ALA4614804	mL.min-1.kg-1
10.	Iptacopan hydrochloride	41.HCl	Tmax	=	2	hr	ALA4614803	hr
11.	Iptacopan hydrochloride	41.HCl	Cmax/dose	=	410	nM	ALA4614802	nM
12.	Iptacopan hydrochloride	41.HCl	F	=	40	%	ALA4614801	%
13.	Iptacopan hydrochloride	41.HCl	AUC/dose	=	2100	nM.hr	ALA4614800	nM.hr
14.	Iptacopan hydrochloride	41.HCl	AUC/dose	=	5200	nM.hr	ALA4614799	nM.hr
15.	Iptacopan hydrochloride	41.HCl	MRT	=	3.4	hr	ALA4614798	hr
16.	Iptacopan hydrochloride	41.HCl	t1/2	=	7	hr	ALA4614797	hr
17.	Iptacopan hydrochloride	41.HCl	Vdss	=	2.3	L/Kg	ALA4614796	L.kg-1
18.	Iptacopan hydrochloride	41.HCl	CL	=	8	ml/min.kg	ALA4614795	mL.min-1.kg-1
19.	Iptacopan hydrochloride	41.HCl	INH	=	55	%	ALA4614785	%	Canis lupus familiaris
20.	Iptacopan hydrochloride	41.HCl	INH	=	100	%	ALA4614784	%	Canis lupus familiaris