| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4643578 | 10; SC-89-VU43 | Activity | 0 | ALA4605869 | Non-Toxic | ||||||
| 2. | ALA4643578 | 10; SC-89-VU43 | Activity | 0 | ALA4605868 | Non-Toxic | ||||||
| 3. | ALA4643578 | 10; SC-89-VU43 | Activity | 0 | ALA4605867 | Toxic | ||||||
| 4. | ALA4643578 | 10; SC-89-VU43 | Activity | 0 | ALA4605866 | Toxic | ||||||
| 5. | ALA4643578 | 10; SC-89-VU43 | IC50 | = | 7.5 | uM | ALA4605858 | 5.12 | nM | Homo sapiens | ||
| 6. | ALA4643578 | 10; SC-89-VU43 | F | = | 62 | % | ALA4605839 | % | ||||
| 7. | ALA4643578 | 10; SC-89-VU43 | Cmax | = | 0.82 | uM | ALA4605838 | nM | ||||
| 8. | ALA4643578 | 10; SC-89-VU43 | AUC | = | 8.7 | uM.hr | ALA4605837 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
| 9. | ALA4643578 | 10; SC-89-VU43 | t1/2 | = | 3.7 | hr | ALA4605836 | hr | ||||
| 10. | ALA4643578 | 10; SC-89-VU43 | Cmax | = | 0.94 | uM | ALA4605835 | nM | ||||
| 11. | ALA4643578 | 10; SC-89-VU43 | AUC | = | 2.8 | uM.hr | ALA4605834 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
| 12. | ALA4643578 | 10; SC-89-VU43 | t1/2 | = | 3.7 | hr | ALA4605833 | hr | ||||
| 13. | ALA4643578 | 10; SC-89-VU43 | Vdss | = | 5.1 | L/Kg | ALA4605832 | L.kg-1 | ||||
| 14. | ALA4643578 | 10; SC-89-VU43 | CL | = | 19 | ml/min.kg | ALA4605831 | mL.min-1.kg-1 | ||||
| 15. | ALA4643578 | 10; SC-89-VU43 | IC50 | = | 0.015 | uM | ALA4605827 | 7.82 | nM | Homo sapiens | ||
| 16. | ALA4643578 | 10; SC-89-VU43 | IC50 | = | 1.3 | uM | ALA4605826 | 5.89 | nM | Homo sapiens | ||
| 17. | ALA4643578 | 10; SC-89-VU43 | IC50 | = | 0.89 | uM | ALA4605825 | 6.05 | nM | Homo sapiens | ||
| 18. | ALA4643578 | 10; SC-89-VU43 | IC50 | 0 | ALA4605859 | Not Active | Homo sapiens | |||||
| 19. | ALA4643578 | 10; SC-89-VU43 | IC50 | = | 0.003 | uM | ALA4605789 | 8.48 | nM | Homo sapiens |
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