| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  WF-47-JS03 | 1; WF-47-JS03 | Activity | 0 | ALA4605852 | Toxic | ||||||
| 2. | WF-47-JS03 | 1; WF-47-JS03 | IC50 | = | 0.5 | uM | ALA4605859 | 6.30 | nM | Homo sapiens | ||
| 3. | WF-47-JS03 | 1; WF-47-JS03 | IC50 | = | 1.2 | uM | ALA4605858 | 5.92 | nM | Homo sapiens | ||
| 4. | WF-47-JS03 | 1; WF-47-JS03 | Activity | 0 | ALA4605857 | Toxic | ||||||
| 5. | WF-47-JS03 | 1; WF-47-JS03 | Activity | 0 | ALA4605856 | Toxic | ||||||
| 6. | WF-47-JS03 | 1; WF-47-JS03 | Activity | 0 | ALA4605855 | Non-Toxic | ||||||
| 7. | WF-47-JS03 | 1; WF-47-JS03 | Activity | 0 | ALA4605854 | Non-Toxic | ||||||
| 8. | WF-47-JS03 | 1; WF-47-JS03 | Activity | 0 | ALA4605853 | Non-Toxic | ||||||
| 9. | WF-47-JS03 | 1; WF-47-JS03 | Cmax | = | 1.1 | uM | ALA4605784 | nM | ||||
| 10. | WF-47-JS03 | 1; WF-47-JS03 | AUC | = | 3.2 | uM.hr | ALA4605783 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
| 11. | WF-47-JS03 | 1; WF-47-JS03 | t1/2 | = | 3.9 | hr | ALA4605785 | hr | ||||
| 12. | WF-47-JS03 | 1; WF-47-JS03 | Vdss | = | 13 | L/Kg | ALA4605787 | L.kg-1 | ||||
| 13. | WF-47-JS03 | 1; WF-47-JS03 | CL | = | 51 | ml/min.kg | ALA4605786 | mL.min-1.kg-1 | ||||
| 14. | WF-47-JS03 | 1; WF-47-JS03 | solubility | = | 48 | uM | ALA4605828 | nM | ||||
| 15. | WF-47-JS03 | 1; WF-47-JS03 | IC50 | = | 0.005 | uM | ALA4605827 | 8.28 | nM | Homo sapiens | ||
| 16. | WF-47-JS03 | 1; WF-47-JS03 | IC50 | = | 1.5 | uM | ALA4605826 | 5.82 | nM | Homo sapiens | ||
| 17. | WF-47-JS03 | 1; WF-47-JS03 | IC50 | = | 0.99 | uM | ALA4605825 | 6.00 | nM | Homo sapiens | ||
| 18. | WF-47-JS03 | 1; WF-47-JS03 | IC50 | = | 0.002 | uM | ALA4605789 | 8.77 | nM | Homo sapiens |
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