| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4645607 | 37 | INH | 0 | ALA4628284 | Not Active | % | Mus musculus | ||||
| 2. | ALA4645607 | 37 | INH | 0 | ALA4628283 | Not Active | % | Mus musculus | ||||
| 3. | ALA4645607 | 37 | INH | 0 | ALA4628282 | Active | % | Mus musculus | ||||
| 4. | ALA4645607 | 37 | INH | 0 | ALA4628281 | Active | % | Mus musculus | ||||
| 5. | ALA4645607 | 37 | MRT | = | 9.4 | hr | ALA4628280 | hr | ||||
| 6. | ALA4645607 | 37 | MRT | = | 3 | hr | ALA4628279 | hr | ||||
| 7. | ALA4645607 | 37 | AUC | = | 12 | ug.hr/ml | ALA4628278 | ng.hr.mL-1 | ||||
| 8. | ALA4645607 | 37 | AUC | = | 18 | ug.hr/ml | ALA4628277 | ng.hr.mL-1 | ||||
| 9. | ALA4645607 | 37 | Drug uptake | = | 0.23 | ug ml-1 | ALA4628272 | ug ml-1 | ||||
| 10. | ALA4645607 | 37 | Drug uptake | = | 0.007 | ug ml-1 | ALA4628274 | ug ml-1 | ||||
| 11. | ALA4645607 | 37 | Tmax | = | 8 | hr | ALA4628276 | hr | ||||
| 12. | ALA4645607 | 37 | Tmax | = | 0.83 | hr | ALA4628275 | hr | ||||
| 13. | ALA4645607 | 37 | Cmax | = | 0.7 | ug ml-1 | ALA4628273 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 14. | ALA4645607 | 37 | Cmax | = | 6.5 | ug ml-1 | ALA4628271 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 15. | ALA4645607 | 37 | solubility | = | 0.79 | ug ml-1 | ALA4628270 | ug.mL-1 | ||||
| 16. | ALA4645607 | 37 | permeability | = | 424 | nm/s | ALA4628269 | nm/s | ||||
| 17. | ALA4645607 | 37 | IC50 | = | 2400 | nM | ALA4628268 | 5.62 | nM | Homo sapiens | ||
| 18. | ALA4645607 | 37 | IC50 | = | 2.2 | nM | ALA4628267 | 8.66 | nM | Mus musculus | ||
| 19. | ALA4645607 | 37 | IC50 | = | 45 | nM | ALA4628266 | 7.35 | nM | Homo sapiens |
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