# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4646118 | 1f | PPB | = | 86.9 | % | ALA4620729 | % | ||||
2. | ALA4646118 | 1f | PPB | = | 90.8 | % | ALA4620728 | % | ||||
3. | ALA4646118 | 1f | PPB | = | 91.9 | % | ALA4620727 | % | ||||
4. | ALA4646118 | 1f | IC50 | > | 10 | uM | ALA4620726 | nM | Homo sapiens | |||
5. | ALA4646118 | 1f | IC50 | > | 10 | uM | ALA4620725 | nM | Homo sapiens | |||
6. | ALA4646118 | 1f | IC50 | = | 9.6 | uM | ALA4620724 | 5.02 | nM | Homo sapiens | ||
7. | ALA4646118 | 1f | IC50 | > | 10 | uM | ALA4620723 | nM | Homo sapiens | |||
8. | ALA4646118 | 1f | IC50 | > | 10 | uM | ALA4620722 | nM | Homo sapiens | |||
9. | ALA4646118 | 1f | IC50 | > | 10 | uM | ALA4620721 | nM | Homo sapiens | |||
10. | ALA4646118 | 1f | t1/2 | > | 180 | min | ALA4620720 | hr | ||||
11. | ALA4646118 | 1f | t1/2 | > | 180 | min | ALA4620719 | hr | ||||
12. | ALA4646118 | 1f | Efficacy | = | 27 | % | ALA4620714 | % | Homo sapiens | |||
13. | ALA4646118 | 1f | Efficacy | = | 8 | % | ALA4620713 | % | Homo sapiens | |||
14. | ALA4646118 | 1f | solubility | = | 28 | uM | ALA4620712 | nM | ||||
15. | ALA4646118 | 1f | solubility | = | 27 | uM | ALA4620711 | nM | ||||
16. | ALA4646118 | 1f | Efficacy | = | 80 | % | ALA4620710 | % | Homo sapiens | |||
17. | ALA4646118 | 1f | Efficacy | = | -107 | % | ALA4620709 | % | Homo sapiens | |||
18. | ALA4646118 | 1f | IC50 | = | 19 | nM | ALA4620706 | 7.72 | nM | Homo sapiens | ||
19. | ALA4646118 | 1f | Kd | = | 0.6 | nM | ALA4620705 | 9.22 | nM | Homo sapiens | ||
20. | ALA4646118 | 1f | EC50 | = | 98 | nM | ALA4620707 | 7.01 | nM | Homo sapiens |