# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4646431 | 34 | Activity | 0 | ALA4630198 | Active | Mus musculus | |||||
2. | ALA4646431 | 34 | Activity | 0 | ALA4630197 | Non-Toxic | ||||||
3. | ALA4646431 | 34 | Activity | <= | 5 | % | ALA4630196 | % | ||||
4. | ALA4646431 | 34 | TGI | 0 | ALA4630195 | Dose-dependent effect | Homo sapiens | |||||
5. | ALA4646431 | 34 | F | = | 59 | % | ALA4630194 | % | ||||
6. | ALA4646431 | 34 | AUC | = | 189 | ng.hr/ml | ALA4630193 | ng.hr.mL-1 | ||||
7. | ALA4646431 | 34 | Cmax | = | 40 | ng/ml | ALA4630192 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
8. | ALA4646431 | 34 | t1/2 | = | 25.3 | hr | ALA4630191 | hr | ||||
9. | ALA4646431 | 34 | Vdss | = | 118 | L/Kg | ALA4630190 | L.kg-1 | ||||
10. | ALA4646431 | 34 | CL | = | 9.7 | L/hr/kg | ALA4630189 | mL.min-1.kg-1 | ||||
11. | ALA4646431 | 34 | Ratio | = | 1000000 | /M/s | ALA4630188 | /M/s | Homo sapiens | |||
12. | ALA4646431 | 34 | Ki | = | 6.1 | nM | ALA4630187 | 8.21 | nM | Homo sapiens | ||
13. | ALA4646431 | 34 | Kinact | = | 0.38 | /min | ALA4630186 | /min | Homo sapiens | |||
14. | ALA4646431 | 34 | GI50 | = | 0.014 | uM | ALA4630185 | nM | Homo sapiens | |||
15. | ALA4646431 | 34 | GI50 | = | 0.037 | uM | ALA4630184 | nM | Homo sapiens | |||
16. | ALA4646431 | 34 | GI50 | = | 0.332 | uM | ALA4630183 | nM | Homo sapiens | |||
17. | ALA4646431 | 34 | GI50 | = | 0.271 | uM | ALA4630182 | nM | Homo sapiens | |||
18. | ALA4646431 | 34 | GI50 | = | 0.078 | uM | ALA4630181 | nM | Homo sapiens | |||
19. | ALA4646431 | 34 | GI50 | = | 0.005 | uM | ALA4630180 | nM | Homo sapiens | |||
20. | ALA4646431 | 34 | GI50 | = | 0.893 | uM | ALA4630169 | nM | Homo sapiens |