# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4647456 | 18 | ED50 | = | 0.25 | mg kg-1 | ALA4742491 | mg.kg-1 | Mus musculus | |||
2. | ALA4647456 | 18 | Efficacy | = | 110 | % | ALA4742490 | % | Homo sapiens | |||
3. | ALA4647456 | 18 | EC50 | = | 14.4 | nM | ALA4742489 | 7.84 | nM | Homo sapiens | ||
4. | ALA4647456 | 18 | INH | = | 0 | % | ALA4627660 | % | Homo sapiens | |||
5. | ALA4647456 | 18 | INH | = | 0 | % | ALA4627659 | % | Homo sapiens | |||
6. | ALA4647456 | 18 | INH | = | 3.3 | % | ALA4627658 | % | Homo sapiens | |||
7. | ALA4647456 | 18 | F | = | 86 | % | ALA4627657 | % | ||||
8. | ALA4647456 | 18 | Vdss | = | 0.9 | L/Kg | ALA4627656 | L.kg-1 | ||||
9. | ALA4647456 | 18 | CL | = | 8.8 | min/ml/kg | ALA4627655 | min/ml/kg | ||||
10. | ALA4647456 | 18 | F | = | 29 | % | ALA4627654 | % | ||||
11. | ALA4647456 | 18 | Vdss | = | 1 | L/Kg | ALA4627653 | L.kg-1 | ||||
12. | ALA4647456 | 18 | CL | = | 40.1 | min/ml/kg | ALA4627652 | min/ml/kg | ||||
13. | ALA4647456 | 18 | Drug metabolism | = | 26 | % | ALA4627651 | % | ||||
14. | ALA4647456 | 18 | Drug metabolism | = | 33 | % | ALA4627650 | % | ||||
15. | ALA4647456 | 18 | Drug metabolism | = | 55 | % | ALA4627649 | % | ||||
16. | ALA4647456 | 18 | Drug metabolism | = | 39 | % | ALA4627648 | % | ||||
17. | ALA4647456 | 18 | Emax | = | 111 | % | ALA4627647 | % | Homo sapiens | |||
18. | ALA4647456 | 18 | EC50 | = | 14 | nM | ALA4627646 | 7.85 | nM | Homo sapiens |