| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4647703 | 66 | Activity | 0 | ALA4605207 | Active | Homo sapiens | |||||
| 2. | ALA4647703 | 66 | Activity | 0 | ALA4605206 | Active | Homo sapiens | |||||
| 3. | ALA4647703 | 66 | Activity | 0 | ALA4605205 | Active | Homo sapiens | |||||
| 4. | ALA4647703 | 66 | Activity | 0 | ALA4605204 | Non-Toxic | ||||||
| 5. | ALA4647703 | 66 | TGI | 0 | ALA4605202 | Dose-dependent effect | Homo sapiens | |||||
| 6. | ALA4647703 | 66 | Activity | 0 | ALA4605201 | Non-Toxic | ||||||
| 7. | ALA4647703 | 66 | Activity | 0 | ALA4605200 | Non-Toxic | ||||||
| 8. | ALA4647703 | 66 | F | = | 28.9 | % | ALA4605199 | % | ||||
| 9. | ALA4647703 | 66 | CL | = | 10.8 | L/hr/kg | ALA4605198 | mL.min-1.kg-1 | ||||
| 10. | ALA4647703 | 66 | AUC | = | 925.7 | ug/L.hr | ALA4605197 | ng.hr.mL-1 | ||||
| 11. | ALA4647703 | 66 | Cmax | = | 100.6 | ug/L | ALA4605196 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 12. | ALA4647703 | 66 | Tmax | = | 4 | hr | ALA4605195 | hr | ||||
| 13. | ALA4647703 | 66 | t1/2 | = | 3.24 | hr | ALA4605194 | hr | ||||
| 14. | ALA4647703 | 66 | CL | = | 3.13 | L/hr/kg | ALA4605193 | mL.min-1.kg-1 | ||||
| 15. | ALA4647703 | 66 | AUC | = | 640.8 | ug/L.hr | ALA4605192 | ng.hr.mL-1 | ||||
| 16. | ALA4647703 | 66 | Cmax | = | 994.7 | ug/L | ALA4605191 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 17. | ALA4647703 | 66 | t1/2 | = | 1.76 | hr | ALA4605190 | hr | ||||
| 18. | ALA4647703 | 66 | IC50 | = | 31.4 | uM | ALA4605189 | 4.50 | nM | Homo sapiens | ||
| 19. | ALA4647703 | 66 | IC50 | > | 50 | uM | ALA4605188 | nM | Homo sapiens | |||
| 20. | ALA4647703 | 66 | IC50 | > | 50 | uM | ALA4605187 | nM | Homo sapiens |
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