# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4647764 | 1d; MFH290 | F | = | 25 | % | ALA4612827 | % | ||||
2. | ALA4647764 | 1d; MFH290 | AUClast | = | 412.44 | hr.ng/ml | ALA4612826 | ng.hr.mL-1 | ||||
3. | ALA4647764 | 1d; MFH290 | Cmax | = | 556.46 | ng/ml | ALA4612825 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
4. | ALA4647764 | 1d; MFH290 | Tmax | = | 0.25 | hr | ALA4612824 | hr | ||||
5. | ALA4647764 | 1d; MFH290 | F | = | 49 | % | ALA4612823 | % | ||||
6. | ALA4647764 | 1d; MFH290 | t1/2 | = | 0.15 | hr | ALA4612822 | hr | ||||
7. | ALA4647764 | 1d; MFH290 | AUClast | = | 393.63 | hr.ng/ml | ALA4612821 | ng.hr.mL-1 | ||||
8. | ALA4647764 | 1d; MFH290 | Cmax | = | 885.05 | ng/ml | ALA4612820 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
9. | ALA4647764 | 1d; MFH290 | Tmax | = | 0.08 | hr | ALA4612819 | hr | ||||
10. | ALA4647764 | 1d; MFH290 | Vdss | = | 730 | ml/kg | ALA4612818 | L.kg-1 | ||||
11. | ALA4647764 | 1d; MFH290 | CL | = | 102.03 | ml/min.kg | ALA4612817 | mL.min-1.kg-1 | ||||
12. | ALA4647764 | 1d; MFH290 | t1/2 | = | 0.17 | hr | ALA4612816 | hr | ||||
13. | ALA4647764 | 1d; MFH290 | AUClast | = | 162.22 | hr.ng/ml | ALA4612815 | ng.hr.mL-1 | ||||
14. | ALA4647764 | 1d; MFH290 | Cmax | = | 1312.89 | ng/ml | ALA4612814 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
15. | ALA4647764 | 1d; MFH290 | INH | 0 | ALA4612813 | Active | % | Homo sapiens | ||||
16. | ALA4647764 | 1d; MFH290 | INH | 0 | ALA4612812 | Not Active | % | |||||
17. | ALA4647764 | 1d; MFH290 | INH | 0 | ALA4612811 | Not Active | % | Homo sapiens | ||||
18. | ALA4647764 | 1d; MFH290 | INH | 0 | ALA4612810 | Not Active | % | |||||
19. | ALA4647764 | 1d; MFH290 | INH | 0 | ALA4612809 | Not Active | % | Homo sapiens | ||||
20. | ALA4647764 | 1d; MFH290 | INH | 0 | ALA4612808 | Not Active | % |