# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4647898 | 12; DS37571084 | F | = | 61 | % | ALA4620815 | % | ||||
2. | ALA4647898 | 12; DS37571084 | AUClast | = | 2.5 | hr.microg/ml | ALA4620814 | ng.hr.mL-1 | ||||
3. | ALA4647898 | 12; DS37571084 | BBB | = | 13.1 | hr | ALA4620813 | hr | ||||
4. | ALA4647898 | 12; DS37571084 | Vdss | = | 29.4 | L/Kg | ALA4620812 | L.kg-1 | ||||
5. | ALA4647898 | 12; DS37571084 | CL | = | 39 | ml/min.kg | ALA4620811 | mL.min-1.kg-1 | ||||
6. | ALA4647898 | 12; DS37571084 | logD | = | 3.5 | ALA4620810 | ||||||
7. | ALA4647898 | 12; DS37571084 | INH | < | 50 | % | ALA4620809 | % | Homo sapiens | |||
8. | ALA4647898 | 12; DS37571084 | INH | < | 50 | % | ALA4620808 | % | Homo sapiens | |||
9. | ALA4647898 | 12; DS37571084 | INH | < | 50 | % | ALA4620807 | % | Homo sapiens | |||
10. | ALA4647898 | 12; DS37571084 | INH | < | 50 | % | ALA4620806 | % | Homo sapiens | |||
11. | ALA4647898 | 12; DS37571084 | INH | < | 50 | % | ALA4620805 | % | Homo sapiens | |||
12. | ALA4647898 | 12; DS37571084 | INH | < | 50 | % | ALA4620804 | % | Homo sapiens | |||
13. | ALA4647898 | 12; DS37571084 | solubility | = | 77 | ug ml-1 | ALA4620803 | ug.mL-1 | ||||
14. | ALA4647898 | 12; DS37571084 | solubility | = | 570 | ug ml-1 | ALA4620802 | ug.mL-1 | ||||
15. | ALA4647898 | 12; DS37571084 | Stability | = | 65 | % | ALA4620801 | % | ||||
16. | ALA4647898 | 12; DS37571084 | IC50 | = | 0.17 | uM | ALA4620800 | 6.77 | nM | Homo sapiens |