| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4740381 | 19a | INH | 0 | ALA4727783 | Not Active | % | Homo sapiens | ||||
| 2. | ALA4740381 | 19a | INH | 0 | ALA4727782 | Not Active | % | Homo sapiens | ||||
| 3. | ALA4740381 | 19a | INH | 0 | ALA4727781 | Not Active | % | Homo sapiens | ||||
| 4. | ALA4740381 | 19a | INH | 0 | ALA4727780 | Not Active | % | Homo sapiens | ||||
| 5. | ALA4740381 | 19a | INH | 0 | ALA4727779 | Not Active | % | Homo sapiens | ||||
| 6. | ALA4740381 | 19a | BPR | = | 0.35 | ALA4727778 | ||||||
| 7. | ALA4740381 | 19a | Drug uptake | = | 84 | ng/g | ALA4727777 | ng/g | ||||
| 8. | ALA4740381 | 19a | Cp | = | 240 | ng/ml | ALA4727776 | ng/ml | ||||
| 9. | ALA4740381 | 19a | F | = | 45.3 | % | ALA4727775 | % | ||||
| 10. | ALA4740381 | 19a | AUC | = | 1289 | hr.ng/ml | ALA4727774 | ng.hr.mL-1 | ||||
| 11. | ALA4740381 | 19a | Tmax | = | 4 | hr | ALA4727773 | hr | ||||
| 12. | ALA4740381 | 19a | Cmax | = | 127.7 | ng/ml | ALA4727772 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 13. | ALA4740381 | 19a | t1/2 | = | 4.7 | hr | ALA4727771 | hr | ||||
| 14. | ALA4740381 | 19a | AUC | = | 489.6 | hr.ng/ml | ALA4727770 | ng.hr.mL-1 | ||||
| 15. | ALA4740381 | 19a | Vdss | = | 7.3 | L/Kg | ALA4727769 | L.kg-1 | ||||
| 16. | ALA4740381 | 19a | Cmax | = | 133.2 | ng/ml | ALA4727768 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 17. | ALA4740381 | 19a | t1/2 | = | 5.9 | hr | ALA4727767 | hr | ||||
| 18. | ALA4740381 | 19a | CL | = | 17.1 | ml/min.kg | ALA4727766 | mL.min-1.kg-1 | ||||
| 19. | ALA4740381 | 19a | Fu | = | 1.8 | % | ALA4727765 | |||||
| 20. | ALA4740381 | 19a | Fu | = | 1.4 | % | ALA4727764 |
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