# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4740968 | 14 | Activity | = | 1.5 | uM | ALA4727499 | uM | ||||
2. | ALA4740968 | 14 | Activity | < | 0.001 | uM | ALA4727498 | uM | ||||
3. | ALA4740968 | 14 | F | = | 43 | % | ALA4727497 | % | ||||
4. | ALA4740968 | 14 | beta t1/2 | = | 4.7 | hr | ALA4727496 | hr | ||||
5. | ALA4740968 | 14 | Vdss | = | 3.1 | L/Kg | ALA4727495 | L.kg-1 | ||||
6. | ALA4740968 | 14 | CL | = | 11 | ml/min.kg | ALA4727494 | mL.min-1.kg-1 | ||||
7. | ALA4740968 | 14 | Cmax | = | 4370 | nM | ALA4727493 | nM | ||||
8. | ALA4740968 | 14 | AUC | = | 36300 | hr.nM | ALA4727492 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
9. | ALA4740968 | 14 | IC50 | > | 5 | uM | ALA4727489 | nM | Homo sapiens | |||
10. | ALA4740968 | 14 | IC50 | < | 0.001 | uM | ALA4727488 | nM | Homo sapiens | |||
11. | ALA4740968 | 14 | IC50 | = | 0.003 | uM | ALA4727486 | 8.52 | nM | Homo sapiens | ||
12. | ALA4740968 | 14 | IC50 | > | 10 | uM | ALA4727485 | nM | Mus musculus | |||
13. | ALA4740968 | 14 | IC50 | = | 0.055 | uM | ALA4727484 | 7.26 | nM | Mus musculus |