# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4742115 | 1m | F | = | 31.1 | % | ALA4714248 | % | ||||
2. | ALA4742115 | 1m | AUC | = | 1584.1 | ng.hr/ml | ALA4714247 | ng.hr.mL-1 | ||||
3. | ALA4742115 | 1m | INH | = | -22.7 | % | ALA4714246 | % | Homo sapiens | |||
4. | ALA4742115 | 1m | INH | = | 31.4 | % | ALA4714245 | % | Homo sapiens | |||
5. | ALA4742115 | 1m | Stabilty | = | 36 | microL/min/mg | ALA4714244 | microL/min/mg | ||||
6. | ALA4742115 | 1m | Stabilty | = | 30 | microL/min/mg | ALA4714243 | microL/min/mg | ||||
7. | ALA4742115 | 1m | permeability | = | 346 | nm/s | ALA4714242 | nm/s | ||||
8. | ALA4742115 | 1m | permeability | = | 111 | nm/s | ALA4714241 | nm/s | ||||
9. | ALA4742115 | 1m | solubility | < | 0.23 | mg/ml | ALA4714240 | ug.mL-1 | ||||
10. | ALA4742115 | 1m | logD | = | 5.01 | ALA4714239 | ||||||
11. | ALA4742115 | 1m | solubility | < | 0.21 | mg/ml | ALA4714238 | ug.mL-1 | ||||
12. | ALA4742115 | 1m | IC50 | = | 9.7 | nM | ALA4714237 | 8.01 | nM | |||
13. | ALA4742115 | 1m | IC50 | > | 10000 | nM | ALA4714233 | nM | Homo sapiens | |||
14. | ALA4742115 | 1m | IC50 | = | 15 | nM | ALA4714232 | 7.82 | nM | Homo sapiens |