| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4742862 | 16 | pIC50 | = | 8.1 | ALA4676155 | 8.10 | nM | Homo sapiens | |||
| 2. | ALA4742862 | 16 | pIC50 | = | 9.5 | ALA4676154 | 9.50 | nM | Homo sapiens | |||
| 3. | ALA4742862 | 16 | Emax | = | 96 | % | ALA4676153 | % | Homo sapiens | |||
| 4. | ALA4742862 | 16 | logD | = | 2.4 | ALA4676152 | ||||||
| 5. | ALA4742862 | 16 | Fu | = | 34 | % | ALA4676151 | |||||
| 6. | ALA4742862 | 16 | CLH | = | 7 | uL/min | ALA4676150 | uL/min | ||||
| 7. | ALA4742862 | 16 | Activity | = | 89 | % | ALA4676148 | % | Homo sapiens | |||
| 8. | ALA4742862 | 16 | Activity | = | 84 | % | ALA4676147 | % | Homo sapiens | |||
| 9. | ALA4742862 | 16 | Papp | = | 1.8 | 10^-6 cm/s | ALA4676146 | 10^-6 cm/s | ||||
| 10. | ALA4742862 | 16 | Ratio | = | 28 | ALA4676145 | ||||||
| 11. | ALA4742862 | 16 | solubility | > | 900 | uM | ALA4676144 | nM | ||||
| 12. | ALA4742862 | 16 | Fu | = | 51 | % | ALA4676143 | |||||
| 13. | ALA4742862 | 16 | Fu | = | 39 | % | ALA4676142 | |||||
| 14. | ALA4742862 | 16 | Fu | = | 22 | % | ALA4676141 | |||||
| 15. | ALA4742862 | 16 | pKa | = | 8.7 | ALA4676140 | ||||||
| 16. | ALA4742862 | 16 | IC50 | = | 1.2 | uM | ALA4676139 | 5.92 | nM | Homo sapiens | ||
| 17. | ALA4742862 | 16 | IC50 | = | 11 | uM | ALA4676138 | 4.96 | nM | Homo sapiens | ||
| 18. | ALA4742862 | 16 | IC50 | = | 9.1 | uM | ALA4676137 | 5.04 | nM | Homo sapiens | ||
| 19. | ALA4742862 | 16 | CL | = | 125 | ml/min.kg | ALA4676136 | mL.min-1.kg-1 | ||||
| 20. | ALA4742862 | 16 | Vdss | = | 71 | L/Kg | ALA4676135 | L.kg-1 |
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