| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4744705 | 4; PQR514 | NOAEL | = | 10 | mg kg-1 | ALA4668305 | mg kg-1 | ||||
| 2. | ALA4744705 | 4; PQR514 | NOAEL | = | 3.6 | mg kg-1 | ALA4668304 | mg kg-1 | ||||
| 3. | ALA4744705 | 4; PQR514 | NOAEL | = | 2.4 | mg kg-1 | ALA4668303 | mg kg-1 | ||||
| 4. | ALA4744705 | 4; PQR514 | MTD | = | 6.3 | mg kg-1 | ALA4668302 | mg kg-1 | ||||
| 5. | ALA4744705 | 4; PQR514 | Activity | 0 | ALA4668301 | Non-Toxic | ||||||
| 6. | ALA4744705 | 4; PQR514 | GI | 0 | ALA4668300 | Active | Homo sapiens | |||||
| 7. | ALA4744705 | 4; PQR514 | Activity | = | 397 | mm3 | ALA4668299 | mm3 | Homo sapiens | |||
| 8. | ALA4744705 | 4; PQR514 | Activity | 0 | ALA4668297 | Active | ||||||
| 9. | ALA4744705 | 4; PQR514 | Activity | 0 | ALA4668296 | Active | ||||||
| 10. | ALA4744705 | 4; PQR514 | BPR | = | 0.3 | ALA4668295 | ||||||
| 11. | ALA4744705 | 4; PQR514 | Ratio Ki | = | 2 | ALA4668294 | Homo sapiens | |||||
| 12. | ALA4744705 | 4; PQR514 | CL | = | 2147 | ml/hr/kg | ALA4668293 | mL.min-1.kg-1 | ||||
| 13. | ALA4744705 | 4; PQR514 | AUC | = | 4526 | hr.ng/ml | ALA4668292 | ng.hr.mL-1 | ||||
| 14. | ALA4744705 | 4; PQR514 | t1/2 | = | 1.6 | hr | ALA4668291 | hr | ||||
| 15. | ALA4744705 | 4; PQR514 | Tmax | = | 0.5 | hr | ALA4668290 | hr | ||||
| 16. | ALA4744705 | 4; PQR514 | Cmax | = | 1808 | ng/ml | ALA4668289 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 17. | ALA4744705 | 4; PQR514 | CL | = | 3519 | ml/hr/kg | ALA4668288 | mL.min-1.kg-1 | ||||
| 18. | ALA4744705 | 4; PQR514 | AUC | = | 2757 | hr.ng/ml | ALA4668287 | ng.hr.mL-1 | ||||
| 19. | ALA4744705 | 4; PQR514 | t1/2 | = | 1.6 | hr | ALA4668286 | hr | ||||
| 20. | ALA4744705 | 4; PQR514 | Tmax | = | 0.5 | hr | ALA4668285 | hr |
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