# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4745031 | 13 | Activity | 0 | ALA4707888 | Dose-dependent effect | Mus musculus | |||||
2. | ALA4745031 | 13 | Activity | 0 | ALA4707886 | Active | Mus musculus | |||||
3. | ALA4745031 | 13 | INH | 0 | ALA4707883 | Active | % | Mus musculus | ||||
4. | ALA4745031 | 13 | INH | 0 | ALA4707882 | Active | % | Mus musculus | ||||
5. | ALA4745031 | 13 | Activity | = | 18.57 | g | ALA4707880 | g | Mus musculus | |||
6. | ALA4745031 | 13 | Activity | = | 19.06 | g | ALA4707879 | g | Mus musculus | |||
7. | ALA4745031 | 13 | Activity | = | 18.11 | g | ALA4707878 | g | Mus musculus | |||
8. | ALA4745031 | 13 | Activity | = | 19.53 | g | ALA4707877 | g | Mus musculus | |||
9. | ALA4745031 | 13 | Activity | 0 | ALA4707875 | Active | Mus musculus | |||||
10. | ALA4745031 | 13 | Activity | 0 | ALA4707874 | Dose-dependent effect | Mus musculus | |||||
11. | ALA4745031 | 13 | AUCt | = | 229.3 | hr.ng/ml | ALA4707873 | ng.hr.mL-1 | ||||
12. | ALA4745031 | 13 | Cmax | = | 102.73 | ng/ml | ALA4707872 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
13. | ALA4745031 | 13 | Tmax | = | 1 | hr | ALA4707871 | hr | ||||
14. | ALA4745031 | 13 | t1/2 | = | 3.3 | hr | ALA4707870 | hr | ||||
15. | ALA4745031 | 13 | Stabilty | = | 57.4 | % | ALA4707869 | % | ||||
16. | ALA4745031 | 13 | CLH | = | 47.5 | ml/min.kg | ALA4707868 | mL.min-1.kg-1 | ||||
17. | ALA4745031 | 13 | CLH | = | 12 | uL/min | ALA4707867 | uL/min | ||||
18. | ALA4745031 | 13 | t1/2 | = | 115.5 | min | ALA4707866 | hr | ||||
19. | ALA4745031 | 13 | Imax | = | 65 | % | ALA4707865 | % | Mus musculus | |||
20. | ALA4745031 | 13 | IC50 | = | 4.93 | uM | ALA4707864 | 5.31 | nM | Mus musculus |