# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4745208 | 29 | Activity | 0 | ALA4667425 | Dose-dependent effect | ||||||
2. | ALA4745208 | 29 | Activity | 0 | ALA4667424 | Dose-dependent effect | ||||||
3. | ALA4745208 | 29 | Activity | 0 | ALA4667423 | Dose-dependent effect | ||||||
4. | ALA4745208 | 29 | Activity | = | 100 | % | ALA4667421 | % | Mus musculus | |||
5. | ALA4745208 | 29 | Activity | = | -32 | % | ALA4667420 | % | ||||
6. | ALA4745208 | 29 | Activity | = | -27 | % | ALA4667419 | % | ||||
7. | ALA4745208 | 29 | Activity | = | -22 | % | ALA4667418 | % | ||||
8. | ALA4745208 | 29 | Activity | = | -49 | % | ALA4667417 | % | ||||
9. | ALA4745208 | 29 | EC50 | = | 0.22 | uM | ALA4667416 | 6.66 | nM | Homo sapiens | ||
10. | ALA4745208 | 29 | Imax | = | 114 | % | ALA4667415 | % | Homo sapiens | |||
11. | ALA4745208 | 29 | Imax | = | 92 | % | ALA4667414 | % | Homo sapiens | |||
12. | ALA4745208 | 29 | EC50 | = | 0.15 | uM | ALA4667413 | 6.82 | nM | Homo sapiens | ||
13. | ALA4745208 | 29 | Ratio EC50 | > | 2500 | ALA4667412 | ||||||
14. | ALA4745208 | 29 | CL free | = | 6 | L/hr/kg | ALA4667411 | mL.min-1.kg-1 | ||||
15. | ALA4745208 | 29 | CL free | = | 2 | L/hr/kg | ALA4667410 | mL.min-1.kg-1 | ||||
16. | ALA4745208 | 29 | Tmax | = | 0.25 | hr | ALA4667409 | hr | ||||
17. | ALA4745208 | 29 | AUClast | = | 3903 | ng.hr/ml | ALA4667408 | ng.hr.mL-1 | ||||
18. | ALA4745208 | 29 | Cmax | = | 3324 | ng/ml | ALA4667407 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
19. | ALA4745208 | 29 | CL | = | 1.65 | L/hr/kg | ALA4667406 | mL.min-1.kg-1 | ||||
20. | ALA4745208 | 29 | CL free | = | 97 | L/hr/kg | ALA4667405 | mL.min-1.kg-1 |