Activities

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Activities

Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Comment	Assay	Assay Organism
1.	ALA4745332	6a	INH		0		ALA4678752	Not Active	%
2.	ALA4745332	6a	INH		0		ALA4678751	Not Active	%
3.	ALA4745332	6a	INH		0		ALA4678750	Active	%
4.	ALA4745332	6a	INH		0		ALA4678749	Active	%
5.	ALA4745332	6a	INH		0		ALA4678747	Active	%	Homo sapiens
6.	ALA4745332	6a	TGI	=	58.2	%	ALA4678746		%	Homo sapiens
7.	ALA4745332	6a	F	=	99.5	%	ALA4678743		%
8.	ALA4745332	6a	AUC	=	187	hr.microg/ml	ALA4678742		ng.hr.mL-1
9.	ALA4745332	6a	AUCt	=	142.6	hr.microg/ml	ALA4678741		ng.hr.mL-1
10.	ALA4745332	6a	Cmax	=	22.5	ug ml-1	ALA4678740	standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW	nM
11.	ALA4745332	6a	t1/2	=	13.7	hr	ALA4678739		hr
12.	ALA4745332	6a	AUC	=	14.6	hr.microg/ml	ALA4678738		ng.hr.mL-1
13.	ALA4745332	6a	AUCt	=	14.33	hr.microg/ml	ALA4678737		ng.hr.mL-1
14.	ALA4745332	6a	Vdss	=	537	ml/kg	ALA4678736		L.kg-1
15.	ALA4745332	6a	CL	=	276	ml/hr/kg	ALA4678735		mL.min-1.kg-1
16.	ALA4745332	6a	t1/2	=	1.36	hr	ALA4678734		hr
17.	ALA4745332	6a	Fu	=	0.3	%	ALA4678733
18.	ALA4745332	6a	Papp	=	37.6	10^-6 cm/s	ALA4678732		10^-6 cm/s
19.	ALA4745332	6a	Papp	=	21.1	10^-6 cm/s	ALA4678731		10^-6 cm/s
20.	ALA4745332	6a	Kinetic_solubility	=	10.29	uM	ALA4678730		nM