| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4746272 | 12 | Activity | 0 | ALA4685356 | Non-Toxic | ||||||
| 2. | ALA4746272 | 12 | Activity | 0 | ALA4685355 | Non-Toxic | ||||||
| 3. | ALA4746272 | 12 | Activity | 0 | ALA4685354 | Active | Mus musculus | |||||
| 4. | ALA4746272 | 12 | Activity | 0 | ALA4685353 | Active | Mus musculus | |||||
| 5. | ALA4746272 | 12 | Activity | 0 | ALA4685352 | Dose-dependent effect | Mus musculus | |||||
| 6. | ALA4746272 | 12 | Activity | 0 | ALA4685351 | Active | Mus musculus | |||||
| 7. | ALA4746272 | 12 | Activity | 0 | ALA4685350 | Active | Mus musculus | |||||
| 8. | ALA4746272 | 12 | F | = | 23.82 | % | ALA4685349 | % | ||||
| 9. | ALA4746272 | 12 | Cmax | = | 2008.21 | ug/L | ALA4685348 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 10. | ALA4746272 | 12 | beta t1/2 | = | 1.52 | hr | ALA4685347 | hr | ||||
| 11. | ALA4746272 | 12 | CLz/F | = | 97.14 | L/hr/kg | ALA4685346 | L/hr/kg | ||||
| 12. | ALA4746272 | 12 | Vz | = | 220.42 | L/Kg | ALA4685345 | L.kg-1 | ||||
| 13. | ALA4746272 | 12 | MRT | = | 1.42 | hr | ALA4685344 | hr | ||||
| 14. | ALA4746272 | 12 | AUC | = | 897.12 | ug/L.hr | ALA4685343 | ng.hr.mL-1 | ||||
| 15. | ALA4746272 | 12 | AUCt | = | 889.42 | ug/L.hr | ALA4685342 | ng.hr.mL-1 | ||||
| 16. | ALA4746272 | 12 | Cmax | = | 8763.23 | ug/L | ALA4685341 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 17. | ALA4746272 | 12 | beta t1/2 | = | 0.47 | hr | ALA4685340 | hr | ||||
| 18. | ALA4746272 | 12 | CLz/F | = | 8.15 | L/hr/kg | ALA4685339 | L/hr/kg | ||||
| 19. | ALA4746272 | 12 | Vz | = | 8.36 | L/Kg | ALA4685338 | L.kg-1 | ||||
| 20. | ALA4746272 | 12 | MRT | = | 0.73 | hr | ALA4685337 | hr |
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