# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4746624 | 22 | TC50 | > | 11.1 | uM | ALA4651372 | uM | Homo sapiens | |||
2. | ALA4746624 | 22 | TC50 | = | 21.9 | uM | ALA4651371 | uM | Homo sapiens | |||
3. | ALA4746624 | 22 | EC50 | = | 0.066 | uM | ALA4651365 | 7.18 | nM | Schistosoma mansoni | ||
4. | ALA4746624 | 22 | EC50 | < | 0.082 | uM | ALA4651364 | nM | Schistosoma mansoni | |||
5. | ALA4746624 | 22 | EC50 | = | 0.085 | uM | ALA4651363 | 7.07 | nM | Schistosoma japonicum | ||
6. | ALA4746624 | 22 | EC50 | = | 0.061 | uM | ALA4651362 | 7.21 | nM | Schistosoma haematobium | ||
7. | ALA4746624 | 22 | Solubility | = | 2.11 | uM | ALA4651361 | nM | ||||
8. | ALA4746624 | 22 | Binding | = | 100 | % | ALA4651358 | % | ||||
9. | ALA4746624 | 22 | Binding | = | 99.93 | % | ALA4651357 | % | ||||
10. | ALA4746624 | 22 | Stability | = | 36.2 | % | ALA4651355 | % | ||||
11. | ALA4746624 | 22 | Lipophilicity | = | 3.63 | = | ALA4651354 | = | ||||
12. | ALA4746624 | 22 | Binding | = | 100 | % | ALA4651353 | % | ||||
13. | ALA4746624 | 22 | Tmax | = | 0.25 | h | ALA4651349 | hr | ||||
14. | ALA4746624 | 22 | Concentration | = | 3.5 | ng/mL | ALA4651348 | ng/mL | ||||
15. | ALA4746624 | 22 | Concentration | = | 0.1 | ng/mL | ALA4651347 | ng/mL | ||||
16. | ALA4746624 | 22 | Half-life | = | 1.92 | h | ALA4651346 | hr | ||||
17. | ALA4746624 | 22 | Volume | = | 5.13 | L/Kg | ALA4651345 | L.kg-1 | ||||
18. | ALA4746624 | 22 | Clearance | = | 4.75 | L/h/Kg | ALA4651344 | L/h/Kg | ||||
19. | ALA4746624 | 22 | AUC | = | 0.105 | h*ug/mL | ALA4651343 | ng.hr.mL-1 | ||||
20. | ALA4746624 | 22 | Bioavailability | = | 7.84 | % | ALA4651342 | % |