# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4747424 | LSHTM-3642 | TC50 | = | 16.6 | uM | ALA4651372 | uM | Homo sapiens | |||
2. | ALA4747424 | LSHTM-3642 | Efficacy | = | 1.84 | % | ALA4651370 | % | Schistosoma mansoni | |||
3. | ALA4747424 | LSHTM-3642 | Concentration | = | 1500 | ng/mL | ALA4651369 | ng/mL | ||||
4. | ALA4747424 | LSHTM-3642 | Concentration | = | 1700 | ng/mL | ALA4651368 | ng/mL | ||||
5. | ALA4747424 | LSHTM-3642 | Age | = | 21 | d | ALA4651367 | d | ||||
6. | ALA4747424 | LSHTM-3642 | Dose | = | 25 | mg/kg | ALA4651366 | mg.kg-1 | ||||
7. | ALA4747424 | LSHTM-3642 | EC50 | = | 0.048 | uM | ALA4651365 | 7.32 | nM | Schistosoma mansoni | ||
8. | ALA4747424 | LSHTM-3642 | EC50 | = | 0.027 | uM | ALA4651364 | 7.56 | nM | Schistosoma mansoni | ||
9. | ALA4747424 | LSHTM-3642 | EC50 | = | 0.389 | uM | ALA4651363 | 6.41 | nM | Schistosoma japonicum | ||
10. | ALA4747424 | LSHTM-3642 | EC50 | = | 0.023 | uM | ALA4651362 | 7.64 | nM | Schistosoma haematobium | ||
11. | ALA4747424 | LSHTM-3642 | Solubility | = | 0.854 | uM | ALA4651361 | nM | ||||
12. | ALA4747424 | LSHTM-3642 | Solubility | = | 197 | uM | ALA4651360 | nM | ||||
13. | ALA4747424 | LSHTM-3642 | Solubility | = | 196 | uM | ALA4651359 | nM | ||||
14. | ALA4747424 | LSHTM-3642 | Binding | = | 99.992 | % | ALA4651357 | % | ||||
15. | ALA4747424 | LSHTM-3642 | Stability | = | 90.2 | % | ALA4651356 | % | ||||
16. | ALA4747424 | LSHTM-3642 | Lipophilicity | = | 5.29 | = | ALA4651354 | = | ||||
17. | ALA4747424 | LSHTM-3642 | Binding | = | 99.99 | % | ALA4651352 | % | ||||
18. | ALA4747424 | LSHTM-3642 | Stability | = | 105 | % | ALA4651351 | % | ||||
19. | ALA4747424 | LSHTM-3642 | Tmax | = | 1 | h | ALA4651349 | hr | ||||
20. | ALA4747424 | LSHTM-3642 | Concentration | = | 298 | ng/mL | ALA4651348 | ng/mL |