# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4749141 | 44 | IC50 | = | 0.003 | uM | ALA4674513 | 8.52 | nM | Homo sapiens | ||
2. | ALA4749141 | 44 | IC50 | = | 0.278 | uM | ALA4674512 | 6.56 | nM | Homo sapiens | ||
3. | ALA4749141 | 44 | IC50 | = | 0.434 | uM | ALA4674511 | 6.36 | nM | Homo sapiens | ||
4. | ALA4749141 | 44 | Fu | = | 38 | % | ALA4674510 | |||||
5. | ALA4749141 | 44 | Papp | = | 0.3 | 10^-6 cm/s | ALA4674509 | 10^-6 cm/s | ||||
6. | ALA4749141 | 44 | Ratio | = | 38.8 | ALA4674507 | ||||||
7. | ALA4749141 | 44 | AUC | = | 39.9 | ng/mL.hr | ALA4674506 | ng.hr.mL-1 | ||||
8. | ALA4749141 | 44 | CL | = | 59.9 | ml/min.kg | ALA4674505 | mL.min-1.kg-1 | ||||
9. | ALA4749141 | 44 | t1/2 | = | 1.09 | hr | ALA4674504 | hr | ||||
10. | ALA4749141 | 44 | Activity | = | 35.59 | % | ALA4674503 | % | Homo sapiens | |||
11. | ALA4749141 | 44 | Activity | = | 36.97 | % | ALA4674502 | % | Homo sapiens | |||
12. | ALA4749141 | 44 | Activity | = | 104.71 | % | ALA4674501 | % | Homo sapiens | |||
13. | ALA4749141 | 44 | Activity | = | 91.82 | % | ALA4674500 | % | Homo sapiens | |||
14. | ALA4749141 | 44 | Activity | = | 99.21 | % | ALA4674499 | % | Homo sapiens | |||
15. | ALA4749141 | 44 | Activity | = | 95.4 | % | ALA4674498 | % | Homo sapiens | |||
16. | ALA4749141 | 44 | Activity | = | 56.59 | % | ALA4674497 | % | Homo sapiens | |||
17. | ALA4749141 | 44 | Activity | = | 21.75 | % | ALA4674496 | % | Homo sapiens | |||
18. | ALA4749141 | 44 | Activity | = | 27.46 | % | ALA4674495 | % | Homo sapiens | |||
19. | ALA4749141 | 44 | Activity | = | 98.77 | % | ALA4674494 | % | Homo sapiens | |||
20. | ALA4749141 | 44 | Activity | = | 40.26 | % | ALA4674493 | % | Homo sapiens |