| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4749200 | 26 | AUCt | = | 4878 | hr.ug/L | ALA4685241 | ng.hr.mL-1 | ||||
| 2. | ALA4749200 | 26 | beta t1/2 | = | 14.3 | hr | ALA4685240 | hr | ||||
| 3. | ALA4749200 | 26 | F | = | 87.5 | % | ALA4685239 | % | ||||
| 4. | ALA4749200 | 26 | CL | = | 0.9 | L/hr/kg | ALA4685238 | mL.min-1.kg-1 | ||||
| 5. | ALA4749200 | 26 | Vdss | = | 3.9 | L/Kg | ALA4685237 | L.kg-1 | ||||
| 6. | ALA4749200 | 26 | AUCt | = | 5576 | hr.ug/L | ALA4685236 | ng.hr.mL-1 | ||||
| 7. | ALA4749200 | 26 | beta t1/2 | = | 3 | hr | ALA4685235 | hr | ||||
| 8. | ALA4749200 | 26 | INH | 0 | ALA4685234 | Dose-dependent effect | % | |||||
| 9. | ALA4749200 | 26 | INH | 0 | ALA4685233 | Dose-dependent effect | % | |||||
| 10. | ALA4749200 | 26 | Ratio IC50 | = | 4 | ALA4685232 | ||||||
| 11. | ALA4749200 | 26 | Ratio IC50 | = | 174 | ALA4685231 | ||||||
| 12. | ALA4749200 | 26 | Ratio IC50 | = | 221 | ALA4685230 | ||||||
| 13. | ALA4749200 | 26 | IC50 | = | 4.3 | nM | ALA4685229 | 8.37 | nM | Homo sapiens | ||
| 14. | ALA4749200 | 26 | IC50 | = | 174 | nM | ALA4685228 | 6.76 | nM | Homo sapiens | ||
| 15. | ALA4749200 | 26 | IC50 | = | 221 | nM | ALA4685227 | 6.66 | nM | Homo sapiens | ||
| 16. | ALA4749200 | 26 | GI50 | = | 33 | nM | ALA4685226 | nM | Homo sapiens | |||
| 17. | ALA4749200 | 26 | IC50 | = | 1 | nM | ALA4685225 | 9.00 | nM | Homo sapiens |
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