# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4750971 | 13x | FC | = | 3 | ALA4688511 | Rattus norvegicus | |||||
2. | ALA4750971 | 13x | FC | = | 3 | ALA4688510 | ||||||
3. | ALA4750971 | 13x | INH | = | 96 | % | ALA4688508 | % | ||||
4. | ALA4750971 | 13x | IC50 | > | 30 | uM | ALA4688507 | nM | Homo sapiens | |||
5. | ALA4750971 | 13x | IC50 | > | 30 | uM | ALA4688506 | nM | Homo sapiens | |||
6. | ALA4750971 | 13x | Activity | 0 | ALA4688505 | Non-Toxic | ||||||
7. | ALA4750971 | 13x | IC50 | > | 30 | uM | ALA4688504 | nM | Homo sapiens | |||
8. | ALA4750971 | 13x | BPR | = | 0.48 | ALA4688502 | ||||||
9. | ALA4750971 | 13x | Cp | = | 53.5 | uM | ALA4688501 | uM | ||||
10. | ALA4750971 | 13x | Drug uptake | = | 25.4 | uM | ALA4688500 | uM | ||||
11. | ALA4750971 | 13x | F | = | 55 | % | ALA4688499 | % | ||||
12. | ALA4750971 | 13x | Vdss | = | 1893 | ml/kg | ALA4688498 | L.kg-1 | ||||
13. | ALA4750971 | 13x | CL | = | 25 | ml/min.kg | ALA4688497 | mL.min-1.kg-1 | ||||
14. | ALA4750971 | 13x | t1/2 | = | 64 | min | ALA4688496 | hr | ||||
15. | ALA4750971 | 13x | AUC | = | 66360 | ng.min/ml | ALA4688495 | ng.hr.mL-1 | ||||
16. | ALA4750971 | 13x | AUC | = | 40454 | ng.min/ml | ALA4688494 | ng.hr.mL-1 | ||||
17. | ALA4750971 | 13x | Tmax | = | 40 | min | ALA4688493 | hr | ||||
18. | ALA4750971 | 13x | Cmax | = | 466 | ng/ml | ALA4688492 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
19. | ALA4750971 | 13x | Activity | = | 5.14 | ml | ALA4688490 | ml | Rattus norvegicus | |||
20. | ALA4750971 | 13x | INH | 0 | ALA4688488 | Active | % | Rattus norvegicus |