# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4751083 | 4 | GI50 | = | 0.24 | uM | ALA4701494 | nM | Homo sapiens | |||
2. | ALA4751083 | 4 | IC50 | = | 3 | uM | ALA4701493 | 5.52 | nM | Homo sapiens | ||
3. | ALA4751083 | 4 | Ratio | = | 2.1 | ALA4701492 | ||||||
4. | ALA4751083 | 4 | Papp | = | 19 | 10^-6 cm/s | ALA4701491 | 10^-6 cm/s | ||||
5. | ALA4751083 | 4 | CLH | = | 59 | microL/min/mg | ALA4701490 | mL.min-1.g-1 | ||||
6. | ALA4751083 | 4 | CLH | = | 28 | uL/min | ALA4701489 | uL/min | ||||
7. | ALA4751083 | 4 | logD | = | 2 | ALA4701488 | ||||||
8. | ALA4751083 | 4 | IC50 | = | 0.31 | nM | ALA4701487 | 9.51 | nM | Homo sapiens | ||
9. | ALA4751083 | 4 | pKa | = | 8.7 | ALA4675697 | ||||||
10. | ALA4751083 | 4 | F | = | 52 | % | ALA4675694 | % | ||||
11. | ALA4751083 | 4 | Vdss | = | 0.6 | L/Kg | ALA4675693 | L.kg-1 | ||||
12. | ALA4751083 | 4 | CL free | = | 174 | ml/min.kg | ALA4675692 | mL.min-1.kg-1 | ||||
13. | ALA4751083 | 4 | Fu | = | 0.12 | ALA4675691 | ||||||
14. | ALA4751083 | 4 | CL | = | 20 | ml/min.kg | ALA4675690 | mL.min-1.kg-1 | ||||
15. | ALA4751083 | 4 | CLH | = | 36 | uL/min | ALA4675689 | uL/min | ||||
16. | ALA4751083 | 4 | F | = | 60 | % | ALA4675688 | % | ||||
17. | ALA4751083 | 4 | Vdss | = | 1 | L/Kg | ALA4675687 | L.kg-1 | ||||
18. | ALA4751083 | 4 | CL free | = | 151 | ml/min.kg | ALA4675686 | mL.min-1.kg-1 | ||||
19. | ALA4751083 | 4 | Fu | = | 0.05 | ALA4675685 | ||||||
20. | ALA4751083 | 4 | CL | = | 6.8 | ml/min.kg | ALA4675684 | mL.min-1.kg-1 |