# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4751466 | GEP44 | Activity | 0 | ALA4713485 | Non-Toxic | ||||||
2. | ALA4751466 | GEP44 | Activity | 0 | ALA4713484 | Active | Suncus murinus | |||||
3. | ALA4751466 | GEP44 | Activity | 0 | ALA4713483 | Active | Suncus murinus | |||||
4. | ALA4751466 | GEP44 | Activity | 0 | ALA4713482 | Active | Rattus norvegicus | |||||
5. | ALA4751466 | GEP44 | Activity | 0 | ALA4713481 | Active | Rattus norvegicus | |||||
6. | ALA4751466 | GEP44 | Activity | = | 5 | % | ALA4713480 | % | Rattus norvegicus | |||
7. | ALA4751466 | GEP44 | Activity | 0 | ALA4713479 | Active | Rattus norvegicus | |||||
8. | ALA4751466 | GEP44 | Activity | 0 | ALA4713478 | Dose-dependent effect | Rattus norvegicus | |||||
9. | ALA4751466 | GEP44 | Activity | = | 71.4 | % | ALA4713477 | % | Rattus norvegicus | |||
10. | ALA4751466 | GEP44 | CLH | = | 32.5 | microL/min/mg | ALA4713475 | mL.min-1.g-1 | ||||
11. | ALA4751466 | GEP44 | t1/2 | = | 136 | min | ALA4713474 | hr | ||||
12. | ALA4751466 | GEP44 | Activity | 0 | ALA4713473 | Not Active | ||||||
13. | ALA4751466 | GEP44 | Activity | 0 | ALA4713472 | Active | ||||||
14. | ALA4751466 | GEP44 | IC50 | = | 113 | nM | ALA4713471 | 6.95 | nM | Homo sapiens | ||
15. | ALA4751466 | GEP44 | EC50 | = | 480 | pM | ALA4713470 | 9.32 | nM | Rattus norvegicus | ||
16. | ALA4751466 | GEP44 | Activity | 0 | ALA4713469 | Not Active | Homo sapiens | |||||
17. | ALA4751466 | GEP44 | Activity | 0 | ALA4713468 | Not Active | Homo sapiens | |||||
18. | ALA4751466 | GEP44 | EC50 | > | 3 | uM | ALA4713467 | nM | Rattus norvegicus | |||
19. | ALA4751466 | GEP44 | IC50 | = | 27 | nM | ALA4713466 | 7.57 | nM | Homo sapiens | ||
20. | ALA4751466 | GEP44 | IC50 | = | 10 | nM | ALA4713465 | 8.00 | nM | Homo sapiens |