| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4751920 | 9; DSM426 | Ratio | = | 1.5 | ALA4706919 | ||||||
| 2. | ALA4751920 | 9; DSM426 | PPB | = | 96.5 | % | ALA4706913 | % | ||||
| 3. | ALA4751920 | 9; DSM426 | PPB | = | 97.4 | % | ALA4706907 | % | ||||
| 4. | ALA4751920 | 9; DSM426 | Activity | 0 | ALA4706905 | Active | Plasmodium falciparum | |||||
| 5. | ALA4751920 | 9; DSM426 | Activity | 0 | ALA4706904 | Active | Plasmodium falciparum | |||||
| 6. | ALA4751920 | 9; DSM426 | Activity | 0 | ALA4706903 | Active | Plasmodium falciparum | |||||
| 7. | ALA4751920 | 9; DSM426 | Activity | 0 | ALA4706902 | Active | Plasmodium falciparum | |||||
| 8. | ALA4751920 | 9; DSM426 | Activity | 0 | ALA4706901 | Active | Plasmodium falciparum | |||||
| 9. | ALA4751920 | 9; DSM426 | Ratio EC50 | > | 600 | ALA4706900 | ||||||
| 10. | ALA4751920 | 9; DSM426 | EC50 | = | 8.6 | uM | ALA4706899 | 5.07 | nM | |||
| 11. | ALA4751920 | 9; DSM426 | fAUC | = | 0.12 | uM.hr | ALA4706898 | uM.hr | ||||
| 12. | ALA4751920 | 9; DSM426 | AUCED90 | = | 10.3 | uM.hr/day | ALA4706872 | uM.hr/day | Plasmodium falciparum | |||
| 13. | ALA4751920 | 9; DSM426 | ED90 | = | 19 | mg kg-1 | ALA4706870 | mg kg-1 | Plasmodium falciparum | |||
| 14. | ALA4751920 | 9; DSM426 | F | = | 67 | % | ALA4706869 | % | ||||
| 15. | ALA4751920 | 9; DSM426 | fAUC | = | 0.89 | uM.hr | ALA4706864 | uM.hr | ||||
| 16. | ALA4751920 | 9; DSM426 | AUC | = | 24.6 | uM.hr | ALA4706859 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
| 17. | ALA4751920 | 9; DSM426 | fCmax | = | 0.12 | uM | ALA4706854 | uM | ||||
| 18. | ALA4751920 | 9; DSM426 | Cmax | = | 3.3 | uM | ALA4706849 | nM | ||||
| 19. | ALA4751920 | 9; DSM426 | Tmax | = | 3.3 | hr | ALA4706846 | hr | ||||
| 20. | ALA4751920 | 9; DSM426 | fVdss | = | 186 | L/Kg | ALA4706841 | L/Kg |
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