# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4752523 | 7 | F | = | 99 | % | ALA4671773 | % | ||||
2. | ALA4752523 | 7 | MRT | = | 3.23 | hr | ALA4671772 | hr | ||||
3. | ALA4752523 | 7 | beta t1/2 | = | 2.35 | hr | ALA4671771 | hr | ||||
4. | ALA4752523 | 7 | Vdss | = | 0.2 | L/Kg | ALA4671770 | L.kg-1 | ||||
5. | ALA4752523 | 7 | AUCt | = | 16452 | ng.hr/ml | ALA4671769 | ng.hr.mL-1 | ||||
6. | ALA4752523 | 7 | Stabilty | 0 | ALA4671768 | Stable | % | |||||
7. | ALA4752523 | 7 | IC50 | = | 35 | nM | ALA4671767 | 7.46 | nM | Homo sapiens | ||
8. | ALA4752523 | 7 | IC50 | = | 26 | nM | ALA4671765 | 7.58 | nM | Homo sapiens | ||
9. | ALA4752523 | 7 | IC50 | = | 24 | nM | ALA4671764 | 7.62 | nM | Homo sapiens | ||
10. | ALA4752523 | 7 | IC50 | = | 33 | nM | ALA4671763 | 7.48 | nM | Homo sapiens | ||
11. | ALA4752523 | 7 | IC50 | > | 10 | uM | ALA4671762 | nM | Homo sapiens | |||
12. | ALA4752523 | 7 | INH | 0 | ALA4671761 | Not Active | % | Homo sapiens | ||||
13. | ALA4752523 | 7 | solubility | 0 | ALA4671760 | Soluble | ||||||
14. | ALA4752523 | 7 | Stabilty | 0 | ALA4671759 | Stable | % | |||||
15. | ALA4752523 | 7 | Stabilty | 0 | ALA4671758 | Stable | % | |||||
16. | ALA4752523 | 7 | permeability | 0 | ALA4671757 | Permeable | ||||||
17. | ALA4752523 | 7 | Stabilty | 0 | ALA4671756 | Stable | % | |||||
18. | ALA4752523 | 7 | Tmax | = | 0.25 | hr | ALA4671755 | hr | ||||
19. | ALA4752523 | 7 | AUCt | = | 48937 | ng.hr/ml | ALA4671754 | ng.hr.mL-1 | ||||
20. | ALA4752523 | 7 | Cmax | = | 8488 | ng/ml | ALA4671753 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM |