# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4753164 | 30 | pKa | = | 7.2 | ALA4675697 | ||||||
2. | ALA4753164 | 30 | Papp | = | 6.5 | 10^-6 cm/s | ALA4675696 | 10^-6 cm/s | ||||
3. | ALA4753164 | 30 | Ratio | = | 16 | ALA4675695 | ||||||
4. | ALA4753164 | 30 | F | = | 7 | % | ALA4675694 | % | ||||
5. | ALA4753164 | 30 | Vdss | = | 8 | L/Kg | ALA4675693 | L.kg-1 | ||||
6. | ALA4753164 | 30 | CL free | = | 955 | ml/min.kg | ALA4675692 | mL.min-1.kg-1 | ||||
7. | ALA4753164 | 30 | Fu | = | 0.27 | ALA4675691 | ||||||
8. | ALA4753164 | 30 | CL | = | 255 | ml/min.kg | ALA4675690 | mL.min-1.kg-1 | ||||
9. | ALA4753164 | 30 | CLH | = | 44 | uL/min | ALA4675689 | uL/min | ||||
10. | ALA4753164 | 30 | F | = | 5 | % | ALA4675688 | % | ||||
11. | ALA4753164 | 30 | Vdss | = | 11 | L/Kg | ALA4675687 | L.kg-1 | ||||
12. | ALA4753164 | 30 | CL free | = | 787 | ml/min.kg | ALA4675686 | mL.min-1.kg-1 | ||||
13. | ALA4753164 | 30 | Fu | = | 0.24 | ALA4675685 | ||||||
14. | ALA4753164 | 30 | CL | = | 189 | ml/min.kg | ALA4675684 | mL.min-1.kg-1 | ||||
15. | ALA4753164 | 30 | CLH | = | 1.9 | uL/min | ALA4675683 | uL/min | ||||
16. | ALA4753164 | 30 | solubility | = | 97 | uM | ALA4675682 | nM | ||||
17. | ALA4753164 | 30 | GI50 | = | 5.3 | uM | ALA4675681 | nM | ||||
18. | ALA4753164 | 30 | Kd | = | 400 | nM | ALA4675680 | 6.40 | nM | Homo sapiens | ||
19. | ALA4753164 | 30 | CLH | = | 12 | uL/min | ALA4675679 | uL/min | ||||
20. | ALA4753164 | 30 | CLH | = | 40 | microL/min/mg | ALA4675678 | mL.min-1.g-1 |