| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4753862 | 13; DSM422 | Ratio | = | 1.5 | ALA4706917 | ||||||
| 2. | ALA4753862 | 13; DSM422 | PPB | = | 97.2 | % | ALA4706911 | % | ||||
| 3. | ALA4753862 | 13; DSM422 | PPB | = | 97.2 | % | ALA4706907 | % | ||||
| 4. | ALA4753862 | 13; DSM422 | Ratio EC50 | > | 600 | ALA4706900 | ||||||
| 5. | ALA4753862 | 13; DSM422 | EC50 | = | 7.4 | uM | ALA4706899 | 5.13 | nM | |||
| 6. | ALA4753862 | 13; DSM422 | fAUC | = | 0.05 | uM.hr | ALA4706896 | uM.hr | ||||
| 7. | ALA4753862 | 13; DSM422 | F | = | 86 | % | ALA4706867 | % | ||||
| 8. | ALA4753862 | 13; DSM422 | fAUC | = | 0.79 | uM.hr | ALA4706862 | uM.hr | ||||
| 9. | ALA4753862 | 13; DSM422 | AUC | = | 28.1 | uM.hr | ALA4706857 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
| 10. | ALA4753862 | 13; DSM422 | fCmax | = | 0.07 | uM | ALA4706852 | uM | ||||
| 11. | ALA4753862 | 13; DSM422 | Cmax | = | 2.7 | uM | ALA4706847 | nM | ||||
| 12. | ALA4753862 | 13; DSM422 | Tmax | = | 3.3 | hr | ALA4706844 | hr | ||||
| 13. | ALA4753862 | 13; DSM422 | fVdss | = | 311 | L/Kg | ALA4706839 | L/Kg | ||||
| 14. | ALA4753862 | 13; DSM422 | Vdss | = | 8.7 | L/Kg | ALA4706834 | L.kg-1 | ||||
| 15. | ALA4753862 | 13; DSM422 | CL free | = | 800 | ml/min.kg | ALA4706829 | mL.min-1.kg-1 | ||||
| 16. | ALA4753862 | 13; DSM422 | CL | = | 22.4 | ml/min.kg | ALA4706824 | mL.min-1.kg-1 | ||||
| 17. | ALA4753862 | 13; DSM422 | AUC | = | 2 | uM.hr | ALA4706819 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
| 18. | ALA4753862 | 13; DSM422 | t1/2(app) | = | 6.1 | hr | ALA4706814 | hr | ||||
| 19. | ALA4753862 | 13; DSM422 | beta t1/2 | = | 2 | hr | ALA4706811 | hr | ||||
| 20. | ALA4753862 | 13; DSM422 | fAUC | = | 0.47 | uM.hr | ALA4706810 | uM.hr |
The page will load shortly, Thanks for your patience!