# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4755173 | 2 | Drug uptake | = | 1.5 | uM | ALA4727501 | uM | ||||
2. | ALA4755173 | 2 | F | = | 0 | % | ALA4727497 | % | ||||
3. | ALA4755173 | 2 | beta t1/2 | = | 5.9 | hr | ALA4727496 | hr | ||||
4. | ALA4755173 | 2 | Vdss | = | 29 | L/Kg | ALA4727495 | L.kg-1 | ||||
5. | ALA4755173 | 2 | CL | = | 165 | ml/min.kg | ALA4727494 | mL.min-1.kg-1 | ||||
6. | ALA4755173 | 2 | Cmax | = | 0 | nM | ALA4727493 | nM | ||||
7. | ALA4755173 | 2 | AUC | = | 0 | hr.nM | ALA4727492 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
8. | ALA4755173 | 2 | IC50 | = | 2.3 | uM | ALA4727489 | 5.64 | nM | Homo sapiens | ||
9. | ALA4755173 | 2 | IC50 | = | 0.026 | uM | ALA4727488 | 7.58 | nM | Homo sapiens | ||
10. | ALA4755173 | 2 | IC50 | = | 0.053 | uM | ALA4727486 | 7.28 | nM | Homo sapiens | ||
11. | ALA4755173 | 2 | IC50 | = | 1.3 | uM | ALA4727485 | 5.89 | nM | Mus musculus | ||
12. | ALA4755173 | 2 | IC50 | = | 0.097 | uM | ALA4727484 | 7.01 | nM | Mus musculus | ||
13. | ALA4755173 | 2 | INH | = | 1544 | nM | ALA4727481 | nM | ||||
14. | ALA4755173 | 2 | INH | = | 1544 | nM | ALA4727480 | nM | ||||
15. | ALA4755173 | 2 | INH | = | 832 | nM | ALA4727479 | nM | ||||
16. | ALA4755173 | 2 | INH | = | 832 | nM | ALA4727478 | nM |