# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4755187 | 6g | Activity | 0 | ALA4727637 | Active | Mus musculus | |||||
2. | ALA4755187 | 6g | Activity | 0 | ALA4727636 | Active | Mus musculus | |||||
3. | ALA4755187 | 6g | INH | 0 | ALA4727635 | Not Active | % | |||||
4. | ALA4755187 | 6g | INH | 0 | ALA4727634 | Active | % | |||||
5. | ALA4755187 | 6g | Activity | 0 | ALA4727633 | Dose-dependent effect | Rattus norvegicus | |||||
6. | ALA4755187 | 6g | Activity | 0 | ALA4727632 | Dose-dependent effect | Rattus norvegicus | |||||
7. | ALA4755187 | 6g | INH | 0 | ALA4727631 | Dose-dependent effect | % | |||||
8. | ALA4755187 | 6g | Activity | = | 0.2 | g | ALA4727630 | g | ||||
9. | ALA4755187 | 6g | Activity | = | 0.002 | g | ALA4727629 | g | ||||
10. | ALA4755187 | 6g | Activity | = | 60.7 | % | ALA4727626 | % | Rattus norvegicus | |||
11. | ALA4755187 | 6g | Activity | = | 38.3 | % | ALA4727625 | % | Rattus norvegicus | |||
12. | ALA4755187 | 6g | F | = | 52.1 | % | ALA4727624 | % | ||||
13. | ALA4755187 | 6g | Tmax | = | 1 | hr | ALA4727623 | hr | ||||
14. | ALA4755187 | 6g | Cmax | = | 4680 | ng/ml | ALA4727622 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
15. | ALA4755187 | 6g | AUC | = | 9158 | hr.ng/ml | ALA4727621 | ng.hr.mL-1 | ||||
16. | ALA4755187 | 6g | t1/2 | = | 0.83 | hr | ALA4727620 | hr | ||||
17. | ALA4755187 | 6g | Vdss | = | 0.96 | L/Kg | ALA4727619 | L.kg-1 | ||||
18. | ALA4755187 | 6g | CL | = | 19 | ml/min.kg | ALA4727618 | mL.min-1.kg-1 | ||||
19. | ALA4755187 | 6g | F | = | 22.3 | % | ALA4727617 | % | ||||
20. | ALA4755187 | 6g | Tmax | = | 0.25 | hr | ALA4727616 | hr |