| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4755729 | (-)-31a | Activity | 0 | ALA4667957 | Non-Toxic | Homo sapiens | |||||
| 2. | ALA4755729 | (-)-31a | INH | = | 65.3 | % | ALA4667955 | % | Plasmodium chabaudi | |||
| 3. | ALA4755729 | (-)-31a | IC50 | = | 89 | nM | ALA4667954 | 7.05 | nM | Plasmodium falciparum | ||
| 4. | ALA4755729 | (-)-31a | IC50 | = | 91 | nM | ALA4667953 | 7.04 | nM | Plasmodium falciparum | ||
| 5. | ALA4755729 | (-)-31a | INH | 0 | ALA4667952 | Not Active | % | Plasmodium falciparum | ||||
| 6. | ALA4755729 | (-)-31a | INH | 0 | ALA4667951 | Not Active | % | |||||
| 7. | ALA4755729 | (-)-31a | IC50 | = | 2572 | nM | ALA4667950 | 5.59 | nM | Homo sapiens | ||
| 8. | ALA4755729 | (-)-31a | INH | 0 | ALA4667949 | Not Active | % | Homo sapiens | ||||
| 9. | ALA4755729 | (-)-31a | Ratio IC50 | = | 28 | ALA4667948 | ||||||
| 10. | ALA4755729 | (-)-31a | IC50 | = | 159 | nM | ALA4667947 | 6.80 | nM | Homo sapiens | ||
| 11. | ALA4755729 | (-)-31a | IC50 | > | 100000 | nM | ALA4667946 | nM | Homo sapiens | |||
| 12. | ALA4755729 | (-)-31a | IC50 | = | 90020 | nM | ALA4667945 | 4.05 | nM | Homo sapiens | ||
| 13. | ALA4755729 | (-)-31a | IC50 | = | 36600 | nM | ALA4667944 | 4.44 | nM | Homo sapiens | ||
| 14. | ALA4755729 | (-)-31a | CL | = | 10.5 | ml/min.kg | ALA4667943 | mL.min-1.kg-1 | ||||
| 15. | ALA4755729 | (-)-31a | IC50 | = | 29400 | nM | ALA4667942 | 4.53 | nM | Homo sapiens | ||
| 16. | ALA4755729 | (-)-31a | t1/2 | = | 7 | hr | ALA4667941 | hr | ||||
| 17. | ALA4755729 | (-)-31a | Vz | = | 6.2 | L/Kg | ALA4667940 | L.kg-1 | ||||
| 18. | ALA4755729 | (-)-31a | Cp | = | 129 | nM | ALA4667936 | nM | ||||
| 19. | ALA4755729 | (-)-31a | Cp | = | 119 | nM | ALA4667935 | nM | ||||
| 20. | ALA4755729 | (-)-31a | Cp | = | 14.9 | nM | ALA4667934 | nM |
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