# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4756083 | 6b | Activity | = | 0.005 | g | ALA4727628 | g | ||||
2. | ALA4756083 | 6b | Activity | = | 0.001 | g | ALA4727627 | g | ||||
3. | ALA4756083 | 6b | Activity | = | 41.4 | % | ALA4727626 | % | Rattus norvegicus | |||
4. | ALA4756083 | 6b | Activity | = | 16 | % | ALA4727625 | % | Rattus norvegicus | |||
5. | ALA4756083 | 6b | F | = | 46.8 | % | ALA4727617 | % | ||||
6. | ALA4756083 | 6b | Tmax | = | 0.31 | hr | ALA4727616 | hr | ||||
7. | ALA4756083 | 6b | Cmax | = | 5245 | ng/ml | ALA4727615 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
8. | ALA4756083 | 6b | AUC | = | 18601 | hr.ng/ml | ALA4727614 | ng.hr.mL-1 | ||||
9. | ALA4756083 | 6b | t1/2 | = | 3.71 | hr | ALA4727613 | hr | ||||
10. | ALA4756083 | 6b | Vdss | = | 0.91 | L/Kg | ALA4727612 | L.kg-1 | ||||
11. | ALA4756083 | 6b | CL | = | 3.92 | ml/min.kg | ALA4727611 | mL.min-1.kg-1 | ||||
12. | ALA4756083 | 6b | Stabilty | = | 94 | % | ALA4727610 | % | ||||
13. | ALA4756083 | 6b | Stabilty | = | 106 | % | ALA4727609 | % | ||||
14. | ALA4756083 | 6b | t1/2 | = | 180 | min | ALA4727608 | hr | ||||
15. | ALA4756083 | 6b | Stabilty | = | 120 | % | ALA4727607 | % | ||||
16. | ALA4756083 | 6b | IC50 | = | 4.2 | nM | ALA4727604 | 8.38 | nM | Homo sapiens | ||
17. | ALA4756083 | 6b | IC50 | = | 93 | nM | ALA4727603 | 7.03 | nM | Homo sapiens |